Kırşehir Ahi Evran Üniversitesi Kurumsal Akademik Arşivi

DSpace@Kırşehir, Kırşehir Ahi Evran Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisimi artırmak için telif haklarına uygun olarak Açık Erişime sunar.


 

Güncel Gönderiler

Öğe
Strait and Product Operations on Strait Soft Sets and their Reduced Soft Matrices with Decision Making Applications
(University of Nis, 2025) Atagün, Akın Osman
In this study, firstly, a new soft set type, common image strait soft sets, which has a special place in the strait soft set structure, is introduced. Common image strait soft sets are strait soft sets whose image is the same partition set of a universal set. A new operation, Strait AND product is defined on both common image strait soft sets and their reduced soft matrices. A multi-criteria group decision-making (MCGDM) problem on performance analysis is described, and a decision-making algorithm is proposed to solve this type of problem, using the Strait AND product of reduced soft matrices of common image strait soft sets. Then the operation Strait AND product defined for common image strait soft sets is generalized for arbitrary strait soft sets. A decision-making algorithm is proposed using the Strait AND product of reduced matrices of arbitrary strait soft sets, and an MCGDM problem is created on market analysis to determine the effect of battery quality of electric cars on sales volume. The validity, advantages and disadvantages of the decision-making method presented in this study are discussed in comparison with the solution of a multi-attribute decision-making (MADM) problem. ©
Öğe
A Novel Hybrid TCN-TE-ANN Model for High-Precision Solar İrradiance Prediction
(PeerJ Inc., 2025) Işık, Murat
As the global community confronts mounting challenges related to environmental sustainability, resource scarcity, and climate change, renewable energy has emerged as a pivotal solution to address these pressing issues.
Öğe
Evaluation of Microbiological Properties in Kefir Production with Fuzzy Logic-Based Decision Support System
(Veteriner Fakultesi Dergisi, 2025) Akıllı, Aslı; Kezer, Gizem; Kul, Ertuğrul
Parallel to rising consumer interest in functional foods, attention to probiotic and natural-content products such as kefir has significantly expanded in recent years. As in all instruments related to food production, the aim in the kefir production process is to obtain a high-quality product, and to ensure the sustainability of production in a healthy manner. In this study, the aim is to develop a fuzzy logic-based decision support system for the quality evaluation of kefir samples categorized into somatic cell and fat (low/high) measurement groups. For this purpose, the system inputs were determined as incubation temperature, incubation time, storage time, total bacterial count, and pH. In the model output, kefir quality indices were calculated for each observation, and quality classes were obtained. In the comparative quality evaluations between the system and expert decisions, the fuzzy logic-based decision support system was found to have achieved a success rate of 93.75%. In addition, the Chi-square statistic and Kappa statistic regarding the decisions made by both the expert and the system were found to be statistically significant (P<0.05). The results indicate that fuzzy logic can be effectively used as a decision support tool in the quality evaluation of kefir samples.
Öğe
Monosodium Glutamate Exposure and Liver Damage: Modulatory Effects of L-Carnitine on Inflammation and Autophagy
(John Wiley and Sons Ltd, 2026) Kalkan, Kübra Tuğçe; Pektaş, Ferhat
Monosodium glutamate (MSG), a widely used flavor enhancer, has been associated with hepatotoxicity through mechanisms involving oxidative stress, inflammatory activation, and disruption of autophagy. L-Carnitine, recognized for its antioxidant and anti-inflammatory effects, has been proposed as a potential therapeutic agent against liver injury. This study aimed to evaluate the hepatotoxic effects of monosodium glutamate (MSG) and the therapeutic potential of L-carnitine in mitigating MSG-induced liver injury, with emphasis on autophagy-related pathways. Forty male offspring obtained from 12 pregnant Wistar albino rats were divided into five groups (n = 8 per group): control, sham, MSG, L-carnitine, and MSG + L-carnitine. Neonatal rats received MSG (4 g/kg, s.c.) on postnatal days 2, 4, 6, 8, and 10, whereas L-carnitine (200 mg/kg, i.p.) was administered between postnatal days 60–81. Biochemical, histopathological, and immunohistochemical analyses were performed. MSG exposure significantly increased serum ALT levels (p < 0.05) and caused marked histological alterations, including cytoplasmic vacuolization (p < 0.001), eosinophilia (p < 0.001), sinusoidal dilatation (p < 0.001), and fibrosis (p < 0.001). [Correction added on 13 January 2026, after first online publication: The phrase “AST (p<0.001) and ALT (p<0.001) levels” has been revised to “ALT levels (p<0.05)” in the previous sentence.] Immunohistochemically, MSG reduced mTOR immunoreactivity by 4% (p < 0.05) while increasing ULK1 by 6% (p < 0.01) and ATG13 by 3.5% (p < 0.05). L-Carnitine treatment significantly decreased histological damage scores (vacuolization −28%, fibrosis −25%, all p < 0.05), restored mTOR levels (p > 0.05 vs. control), and attenuated ULK1 and ATG13 overexpression (p < 0.01). These findings demonstrate that L-carnitine exerts a therapeutic effect against MSG-induced hepatocellular injury by modulating oxidative stress, inflammatory cytokines, and autophagy imbalance via the mTOR–ULK1–ATG13 pathway.
Öğe
Food Diplomacy in Times of Global Crisis: Türkiye’s Mediation Role Through the Black Sea Grain Initiative in Ukraine-Russia War
(Springer Science+Business Media, 2025) Çelenk, Bengü; Güneş, Burak
The primary purpose of this chapter is to examine how Türkiye’s mediation role through the Black Sea Grain Initiative has become a public diplomacy tool in ensuring the sustainability of global food security. The Black Sea Grain Initiative, during the Russian invasion of Ukraine, ensured the export of approximately 32.9 million tons of food from Ukraine between 2022 and 2023, with the mediation of Türkiye and the United Nations (UN). In addition to its North Atlantic Treaty Organization (NATO) membership and relationships with Russia, Türkiye’s control of the straits leading to the Black Sea required its active participation to reach such an agreement. What made solving the food crisis important compared to other problems? The Food and Agriculture Organization (FAO) underlines the need to meet four criteria (availability, access, utilisation, and stability) to address food security, one of humanity’s necessities. However, in recent years, the global food chain has been seriously affected due to economic problems, climate change, COVID-19, and the Russo-Ukrainian War, causing extreme insecurity, particularly in countries that depend on food imports. The war exacerbated the upward trend in global food prices, which had already begun following the pandemic. The fact that Ukraine, one of the world’s highest grain exporters, was unable to use the sea route, and Russia’s freeze of food shipments, posed a huge risk to countries that rely on imports and require humanitarian assistance. In this sense, the Black Sea Grain Initiative aimed at preventing the rise in hunger and food prices. The Russo-Ukrainian War has a negative impact on international politics in many ways. The food crisis that developed due to the war resonated in international politics at least as much as the war, and the international community, including Russia and Ukraine, was able to find common ground for its solution. This study will concentrate on the role of mediation in international law, as well as Türkiye’s portrayal in international press and at the United Nations.