Kırşehir Ahi Evran Üniversitesi Kurumsal Akademik Arşivi
DSpace@Kırşehir, Kırşehir Ahi Evran Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisimi artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Aetiology, Clinical Characteristics, and Risk Factors İnfluencing Mortality in Patients with İnfective Endocarditis: A Retrospective Study
(Taylor and Francis Ltd., 2025) Vural, Özkan; Yılmaz, Özcan; Gedikli, Ömer; Taş, Alperen
Introduction: Infective endocarditis is defined as an infection of the endothelial surfaces in the heart (valves and endocardium), prosthetic heart valves, and intracardiac devices (such as pacemaker leads and ventricular assist devices). Due to diagnostic challenges, determining the true incidence of infective endocarditis is difficult. Despite advancements in diagnosis and treatment, incidence and mortality rates have not decreased. In this study, we evaluated the clinical and laboratory parameters of patients with infective endocarditis followed in our hospital between 2005 and 2018 and assessed their relationship with in-hospital and one-year mortality. Methods: This study retrospectively analysed 145 patients aged ≥18 years who were diagnosed with infective endocarditis and followed in our hospital between 2005 and 2018. Data were analysed using IBM SPSS V23. Statistical analyses included the Shapiro-Wilk test, T-test, Mann-Whitney U test, and Chi-square test. Results: The average age of the patients was 53 (18–86), and 52.4% (n = 76) were male. In 34% (n = 37) of our patients, the predisposing factor for infective endocarditis was rheumatic valve disease. In-hospital mortality was 31.7%, and one-year mortality was 40.6%. A statistically significant difference in in-hospital mortality was found between combination therapy (23%) and medical therapy (40.8%). Mitral valve involvement was the most common, occurring in 48.3% of patients. Staphylococci were the most frequently isolated microorganisms in blood cultures (41.4%). Heart failure was the most common complication and was associated with the highest mortality rate (23.4%). NYHA was an independent predictor of in-hospital mortality. Conclusion: In our study, surgical intervention, i.e. combination therapy, applied after two weeks of antibiotic treatment, was found to be more effective. Early combination therapy may be life-saving.
The Changing Perceptions of Virtual Reality Technology Amongst Elementary School Teacher Candidates
(Routledge, 2026) Atal, Deniz; Sancar, Raziye
This research aims to reveal the changing perceptions of elementary school teacher candidates who participated in online virtual reality (VR) training. The research consists of a qualitative study of 30 elementary school teacher candidates. Data was collected at the start of the course using a demographic information form and an online opinion form. The teacher candidates in the study participated in four-day online courses and recompleted the same opinion form at the end. The data was analysed by the deductive content analytical method. It was found from the research that elementary school teacher candidates had developed basic technical abilities and a profound awareness of VR technology in their future teacher training. It was also concluded that the training given to the classroom teacher candidates is effective in developing an innovative perspective and raising awareness of how VR can be incorporated in teaching.
Impact of Artificial İntelligence and Technology Leadership on Professional Teacher Development
(Routledge, 2025) Işık, Metin
A mixed-methods approach was employed to investigate how balancing technological leadership with AI advancements is essential, considering its perceived usefulness (PU) and perceived ease of use (PEOU) by the application of the Technology Acceptance Model (TAM) and transformational leadership (TL) theory. The study utilized the TAM and Multifactor Leadership Questionnaire to measure the impact of PU and PEOU on Turkish universities. Using SPSS, correlation analysis revealed a strong and positive correlation between PU (r = 0.769**), PEoU (r = 0.865**), TL theory (r = 0.941**), and Professional Teacher Development (PTD). The impact of the factors facilitating technology leadership and AI integration PEoU (p = 0.000) and transformational leadership (p = 0.000) is significant on PTD. In contrast, the impact of PU (p = 0.102) is insignificant on PTD. The AI-driven learning path for teachers’ improvement is improved with the ability to integrate AI competence and improve the PTD outcomes.
First Report on the Molecular Characterization and Phylogenetic Analysis of Fannia Sp. (Diptera: Fanniidae) İdentified in Türkiye
(Sociedade Brasileira De Entomologia, 2025) Ercan, Nuri
This study provides the first data on the molecular characterization and phylogenetic analysis of Fannia sp. specimens collected from livestock farms in Kırşehir province, Türkiye. Two molecular markers, the mitochondrial DNA COI gene and the partial region of the internal transcribed spacer 2 (ITS2) gene, were used for the molecular characterization of the specimens. All COI sequences were identical, representing a single haplotype. Similarly, all ITS2 sequences were identical, representing a single genotype. The BLASTn analysis of the Turkish Fannia COI haplotype showed 100% similarity to Fannia canicularis haplotypes from Portugal, Spain, China, Finland, India, South Korea, Poland, and Canada, and to Fannia subpubescens Collin, 1958 from Finland, and Fannia sp. from Canada, suggesting these are likely F. canicularis. The COI barcode region successfully separated the Fannia species into monophyletic clusters in ML and BI analysis. Besides, the BLASTn analysis of the Turkish Fannia ITS2 genotype revealed lower similarity (64.2% - 88.4%) to ITS2 sequences from other Fannia species. These findings suggest that the mitochondrial COI barcode region is a reliable marker for differentiating the Fannia species. Further studies are needed to elucidate the genetic diversity and epidemiology of these flies in Türkiye.
Development of Chitosan–Hydroxyapatite Membranes from Bone of Armoured Catfish (Pterygoplichthys spp.) for Applications in Guided Bone Regeneration (GBR)
(Multidisciplinary Digital Publishing Institute (MDPI), 2025) López, Ricardo de Jesús Figueroa; Luna-Domínguez, Carlos Roberto; Mendoza-Martínez, Ana María; Şahin, Muradiye; Al-Anzi, Bader Shafaqa; ...; Luna-Domínguez, Jorge Humberto
Nowadays, there is an increasing interest in the development of novel bioresorbable membranes for Guided Bone Regeneration (GBR), and for this purpose, hydroxyapatite, from different sources, has been tested in combination with chitosan. This work details the production and the characterization of membranes of chitosan reinforced with hydroxyapatite derived from the bone of armoured catfish (Pterygoplichthys spp.), which is a widely available natural resource. The hydroxyapatite was characterized morphologically and chemically after the particles of hydroxyapatite were incorporated into a chitosan matrix. Then, the impact of adding hydroxyapatite particles into a matrix of chitosan on the roughness, mechanical properties, degradation, and cytotoxicity was evaluated. Subsequently, an in vivo test was carried out with the purpose of elucidating its guided bone regeneration activity, where the newly developed chitosan–hydroxyapatite membranes were implanted in rabbits with calvarial bone defects. The membranes of chitosan–hydroxyapatite presented a very rough surface morphology compared to the membranes of chitosan; moreover, the membranes of chitosan–hydroxyapatite showed superior mechanical tensile properties. The Masson’s trichrome staining analysis histologically demonstrated that the membranes of chitosan–hydroxyapatite enhanced the formation of a complete mineralized bone matrix in the calvarial bone defects. Finally, these findings confirm that the bone of armoured catfish (Pterygoplichthys spp.) is a viable, economic, and environmentally friendly source for isolating hydroxyapatite, which, combined with a matrix of chitosan, can be a suitable alternative to develop biocompatible GBR membranes.
