Voltammetric Behavior of Telmisartan and Cathodic Adsorptive Stripping Voltammetric Method for Its Assay in Pharmaceutical Dosage Forms and Biological Fluids
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Electrochemical behavior of Telmisartan and optimum conditions for its assay were investigated by using cyclic voltammetry and square-wave voltammetry. All studies were based on the quasi-reversible and adsorption-controlled electrochemical reduction signal of TS at about -1.50 V versus Ag/AgCl at pH 10.0 in Britton-Robinson buffer. The peak current was found to change linearly with concentration from 1.69 nM (0.87 mu g/L) to 27.5 nM (14.15 mu g/L). The limit of detection and the limit of quantification were found to be 1.05 nM (0.54 mu g/L) and 3.49 nM (1.79 mu g/L), respectively. The method was successfully applied to different samples with good recoveries at about 100%.