Yazar "Özel, Merve" için listeleme
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SAHA induce hippo pathway in CCA cells without increasing cell proliferation
Özel, Merve; Başkol, Gülden; Başkol, Mevlüt; Güneş, Fatma; Uçar, Çiğdem; Doğru, Büşra Nur; Akalın, Hilal (Springer Science and Business Media B.V., 2022)Background: Cholangiocarcinoma is a malignant tumor originating from bile duct epithelial cells. Since tumor metastasis is associated with poor prognosis and short-term survival of patients, there is an urgent need for ... -
Suberoylanilide hydroxamic acid inhibits LX2 cells proliferation via decreasing yes-associated protein/transcriptional coactivator with PDZ-binding motif proteins
Özel, Merve; Güçlü, Kenan; Helvacı, Nazlı; Kılıç, Eser; Başkal, Mevlüt; Başkal, Gülden (De Gruyter Open Ltd, 2021)Background: Hepatic fibrosis is a complex and dynamic process similar to “wound healing” that results in the progressive accumulation of connective tissue. We aimed to investigate the epigenetic control of liver fibrosis ...