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Sublingual buprenorphine/naloxone treatment is not affected by OPRM1 A118G and BDNF Va66Met polymorphisms, but alters the plasma beta-endorphin and BDNF levels in individuals with opioid use disorder
Kaya-Akyüzlü, Dilek; Özkan-Kotiloğlu, Selin; Bal, Ceylan; Avcıoğlu, Gamze; Şahiner, Şafak Yalçın; Şahiner, İsmail Volkan (Elsevier B.V., 2022)The study aimed to examine the genetic contribution to buprenorphine (BUP) treatment in individuals with opioid use disorder (OUD), with a specific focus on BDNF and OPRM1 genes. A total of 113 controls and 111 OUD patients ...