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Synthesis, characterization, DFT studies of piperazine derivatives and its Ni(II), Cu(II) complexes as antimicrobial agents and glutathione reductase inhibitors

Ozbek, Neslihan; Mamas, Serhat; Erdogdu, Turkan; Alyar, Saliha; Kaya, Kerem; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2018)

1,4-Piperazinediacetic acid and 1,4-diethyl ester (1) were prepared by treating 1,4-piperazine with ethylchloroacetate; and its structure was identified by single crystal X-ray diffraction analysis. Then, 1,4piperazinediacetic ...