Yazar "Gündoğdu, Özlem" için listeleme
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Evaluation of isoindole derivatives: Antioxidant potential and cytotoxicity in the HT-29 colon cancer cells
Kılıç Süloğlu, Aysun; Selmanoğlu, Güldeniz; Gündoğdu, Özlem; Kishalı, Nurhan H.; Girgin, Gözde; Palabıyık, Sezin; Tan, Ayşe; Kara, Yunus; Baydar, Terken (Wiley-VCH Verlag, 2020)Norcantharimides have an isoindole skeleton structure, and some isoindoline derivatives have positive effects on inflammatory pathologies, including cancers. The present study aims to evaluate the antioxidant and cytotoxic ... -
Regio- and stereo-chemical ring-opening reactions of the 2,3-epoxy alcohol derivative with nucleophiles: Explanation of the structures and C-2 selectivity supported by theoretical computations
Gündoğdu, Özlem; Atalay, Abdurrahman; Çelebioğlu, Neslihan; Anıl, Barış; Şahin, Ertan; Şanlı-Mohamed, Gülşah; Bozkaya, Uğur; Kara, Yunus (Elsevier, 2022)The ring-opening reactions of (1aS,2S,6bR)-5-ethyl-2-hydroxyhexahydro-4H-oxireno[2,3-e]isoindole-4,6(5H)-dione were investigated under very mild and nonchelated conditions. C-2 selective ring-opening products were obtained ... -
Synthesis of new trisubstituted hexahydro-isoindole-1,3-dione derivatives regio- and stereoselectivity: spectroscopic and theoretical studies
Gündoğdu, Özlem (Sprınger Int Publ Ag, 2023)2-Hydroxy-5-alkylhexahydro-4H-oxireno[2,3-e]isoindole-4,6(5H)-diones were synthesized, and their C-2 selective ring opening products were obtained through nucleophilic additions such as with MeOH. The methoxydiols obtained ...
