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Mechanistic Insights into the Reaction of N-Propargylated Pyrrole- and Indole-Carbaldehyde with Ammonia, Alkyl Amines, and Branched Amines: A Synthetic and Theoretical Investigation
Sari, Ozlem; Seybek, Ali Fatih; Kaya, Serdal; Menges, Nurettin; Erdem, Safiye Sag; Balci, Metin (WILEY-V C H VERLAG GMBH, 2019)The reaction of pyrrole- and indole-carbaldehydes having a propargyl group attached to the nitrogen atom with various amines was studied. The reaction with ammonia formed pyrrolo[1,2-a]pyrazine and pyrazino[1,2-a]indole ...