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Synthesis of Benzoxazole-2-carboxylate Derivatives: Electronic- and Position-effect of Functional Groups and Computational Modeling of the Selectivity for Oxazole Ring

Kuzu, Burak; Sarı, Özlem; Erdem, Safiye Sağ; Algül, Öztekin; Mengeş, Nurettin (John Wiley and Sons Inc, 2021)

In this study, Mitsunobu reagent, DEAD (diethyl azodicarboxylate) and PPh3, and ethyl-oxalamide derivatives of 2-aminophenol were reacted under mild reaction conditions. As a result of the cyclization reaction, benzoxazole ...