Yazar "Ozatik, Orhan" için listeleme
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Bone Marrow Mesenchymal Stem Cell Transplantation Enhances Nerve Regeneration in a Rat Model of Hindlimb Replantation
Abbas, Ozan Luay; Ozatik, Orhan; Gonen, Zeynep Burcin; Kocman, Atacan Emre; Dag, Ilknur; Ozatik, Fikriye Yasemin; Bahar, Dilek (LIPPINCOTT WILLIAMS & WILKINS, 2019)Background: Successful limb replantation must be based not only on the viability of the amputated part but also on satisfactory long-term functional recovery. Once the vascular, skeletal, and soft-tissue problems have been ... -
Can a Small Intestine Segment Be an Alternative Biological Conduit for Peripheral Nerve Regeneration?
Arda, Mehmet S.; Kocman, Emre A.; Ozkara, Emre; Soztutar, Erdem; Ozatik, Orhan; Kose, Aydan; Cetin, Cengiz (GALENOS YAYINCILIK, 2017)Background: Autologous nerve grafts are used to bridge peripheral nerve defects. Limited sources and donor site morbidity are the major problems with peripheral nerve grafts. Although various types of autologous grafts ... -
The Effect of Decompression on The Treatment of Chronic Constriction Injury in Peripheral Nerve
Ozatik, Orhan; Kocman, Atacan Emre; Dag, Ilknur; Kose, A. Aydan; Musmul, Ahmet; Sengel, Tayfun (KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2016)Chronic constriction injury (CCI) is a common clinical entity and characterized by allodynia or spontaneous neuropathic pain. Treatment of neuropathic pain is difficult, because a lack of knowledge about the underlying ... -
The effect of sperm activation on pinopod formation in endometrial epithelium
Ozatik, Orhan; Mungan, M. Tamer; Dag, Ilknur; Musmul, Ahmet (ELSEVIER SCIENCE BV, 2016)Introduction: Endometrial receptivity is crucial in implantation of the developing embryo in the endometrium and formation of the pregnancy. In this study, possible effect of sperm and uterine endometrial contact on formation ... -
The effects of iloprost and alprostadil on ischemia-reperfusion injury in preventing inflammation, tissue degeneration, and apoptosis in rat skeletal muscle
Guneysu, Elif; Kocman, Atacan Emre; Ozatik, Orhan; Ovali, Cengiz; Can, Betul; Alatas, Ibrahim Ozkan; Sevin, Mustafa Behcet (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2017)Background/aim: The protective effects of prostaglandin (PG) analogs on ischemia-reperfusion (I/R) have been well documented; however, comparative studies are lacking. The aim of the present study was to determine whether ... -
Enhancement of vascular endothelial growth factor's angiogenic capacity by the therapeutic modulation of notch signalling improves tram flap survival in rats submitted to nicotine
Abbas, Ozan Luay; Terzi, Yunus Kasim; Ozatik, Orhan; Ozatik, Fikriye Yasemin; Turna, Gamze; Nar, Rukiye; Musmul, Ahmet (TAYLOR & FRANCIS LTD, 2017)Background: Smoke of cigarettes, and specifically nicotine, has been shown to diminish pedicled transverse rectus abdominis musculocutaneous (TRAM) flap survival. Considering that Notch signalling through its ligand ... -
Estrogen modulating effects of resveratrol in female rats
Ozatik, Fikriye Yasemin; Erol, Kevser; Ozatik, Orhan (MARMARA UNIV, FAC MEDICINE, 2016)Objectives: This study investigates the estrogen-like effects of resveratrol (RES) in female rats. Materials and Methods: In this two-step study on estrogenlike activity of RES, immature female rats (21 days old) were used ... -
Estrogen-like Activity of Quercetin in Female Rats
Yigitaslan, Semra; Erol, Kevser; Ozatik, Fikriye Yasemin; Ozatik, Orhan; Sahin, Sabiha; Cengelli, Cigdem (AVES, 2016)Objective: Quercetin is a phytoestrogen that exerts both in vitro agonistic and antagonistic activities on estrogen receptors. The present study evaluated the in vivo estrogen-like activity of quercetin on the reproductive ... -
Nerve Tissue Prefabrication Inside the Rat Femoral Bone: Does It Work?
Ozbek, Zuhtu; Kocman, Atacan Emre; Ozatik, Orhan; Soztutar, Erdem; Ozkara, Emre; Kose, Aydan; Arslantas, Ali (TURKISH NEUROSURGICAL SOC, 2017)AIM: To investigate whether nerve regeneration can be induced in the tubular bone between distal and proximal cut nerve ends. MATERIAL and METHODS: Twenty adult Wistar rats were used for the study. Rats were divided into ... -
The Notch Signaling System Is Involved in the Regulation of Reparative Angiogenesis in the Zone of Stasis
Abbas, Ozan Luay; Ozatik, Orhan; Terzi, Yunus Kasim; Ozatik, Fikriye Yasemin; Nar, Rukiye; Turna, Gamze (LIPPINCOTT WILLIAMS & WILKINS, 2017)The Notch pathway ligand Delta-like 4 (Dll4) functions as an antiangiogenic factor, inhibiting vascular endothelial growth factor (VEGF)-induced angiogenesis. This function is documented in tumor and embryonic vasculature. ... -
Prevention of Burn Wound Progression by Mesenchymal Stem Cell Transplantation: Deeper Insights Into Underlying Mechanisms
Abbas, Ozan Luay; Ozatik, Orhan; Gonen, Zeynep Burcin; Ogut, Serdal; Entok, Emre; Ozatik, Fikriye Yasemin; Bahar, Dilek (LIPPINCOTT WILLIAMS & WILKINS, 2018)Introduction Burns are dynamic wounds that may present a progressive expansion of necrosis into the initially viable zone of stasis. Therefore, salvage of this zone is a major subject of focus in burn research. The beneficial ... -
Protective role of resveratrol on testicular germ cells in mice with testicular toxicity
Ozatik, Fikriye Yasemin; Ozatik, Orhan; Yigitaslan, Semra; Unel, Cigdem Cengelli; Erol, Kevser (AVES, 2017)Objective: The aim of the present study was to investigate the possible beneficial effects of resveratrol in mice subjected to vinyl cyclohexene dieposide (VCD) -induced testicular toxicity. Material and methods: A total ...