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Facile synthesis of novel 7-aminofuro- and 7-aminothieno[2,3-d]pyridazin-4(5H)-one and 4-aminophthalazin-1(2H)-ones
Koza, Gani; Keskin, Selbi; Ozer, Merve Sinem; Cengiz, Betul; Sahin, Ertan; Balci, Metin (PERGAMON-ELSEVIER SCIENCE LTD, 2013)We hereby report the synthesis of a novel class of compounds, 7-aminofuro- and 7-aminothieno[2,3-d]pyridazin-4(5H)-one and 4-aminophthalazin-1(2H)-ones starting from methyl 2-(2-methoxy-2-oxoethyl)furan- and thiophene-3- ... -
Furo- and thieno-fused 1,3-diazepine-4,6-diones
Ozer, Merve Sinem; Koza, Gani; Sahin, Ertan; Balci, Metin (PERGAMON-ELSEVIER SCIENCE LTD, 2013)We report the first preparation of furo- and thieno-fused 1,3-diazepine-4,6-dione derivatives starting from ethyl 2-(2-methoxy-2-oxoethyl)-3-furancarboxylate and -thiophencarboxylate. The ester functionalities connected ... -
Intermolecular heterocyclization of alkynones with 2-mercaptoacetaldehyde under metal-free conditions: synthesis of 2,3-disubstituted thiophenes
Vatansever, Erol Can; Kilic, Kubra; Ozer, Merve Sinem; Koza, Gani; Menges, Nurettin; Balci, Metin (PERGAMON-ELSEVIER SCIENCE LTD, 2015)A concise and regioselective approach for the synthesis of 2,3-disubstituted thiophene derivatives has been developed. The synthetic strategy relies on the reaction of an in situ generated 2-mercaptoacetaldehyde with various ...
