Browsing by Author "Çankaya, Nevin"
Now showing items 1-5 of 5
-
Antiproliferative activity and interaction with proteins of N-cyclohexylacrylamide
Çankaya, Nevin; Yalçın, Serap (Elsevier B.V., 2022)N-cyclohexylacrylamıde (NCA), the synthesized compound, was evaluated for their cytotoxic activities against HeLa cancer cell line. Also, the current study has been analyzed by the use of molecular docking as protein-ligand ... -
First Report of the Synthesis, Characterization, DFT Calculations of the New Oxoethyl Methacrylate and o-Acetamide and Evaluation of Antimicrobial, Antibiofilm and Antioxidant Effect
Çankaya, Nevin; Korcan, Safiye Elif; Turan, Nevin; Aydın, Büşra; Tanış, Emine (Taylor and Francis Ltd., 2022)In this study, 2-chloro-N-(2-methoxyphenyl)acetamide (o-acetamide) and 2-(2-methoxyphenylamino)-2-oxoethyl methacrylate (2MPAEMA), which is unreported in the literature were synthesized and characterized. Characterization ... -
The molecular interaction of human anti-apoptotic proteins and in silico ADMET, drug-likeness and toxicity computation of N-cyclohexylmethacrylamide
Çankaya, Nevin; Azarkan, Serap Yalçın; Tanış, Emine (TAYLOR & FRANCIS INC,, MAR 2021)Cancer is an uncontrolled growth of normal cells and apoptosis has an important role in cancer progression and cancer treatment. Antiapoptotic proteins are overexpressed in several tumors including breast, brain, lung ... -
New Syntheses of 4NPMA Homopolymer and Its Copolymer with Limonene: Experimental Analysis and Density Functional Theory Study
Çankaya, Nevin; Tanış, Emine; Sapan, Pembe Gül (Pleiades journals, 2021)Abstract: The N-(4-nitrophenyl)methacrylamide homopolymer (poly(4NPMA)) and copolymer of limonene with N-(4-nitrophenyl)methacrylamide (4NPMA-co-LIM) have been synthesized and characterized by FT-IR and NMR spectroscopic ... -
Synthesis, Characterization, Biological Evaluation and Molecular Docking Studies of New Oxoacrylate and Acetamide on HeLa Cancer Cell Lines
Çankaya, Nevin; Izdal, Mehmetcan; Azarkan, Serap Yalçın (Bentham Scıence Publ Ltd, 2021)Background: In recent years, the discovery and development of new drugs play a critical role in cancer therapy.Objective: In this study, the effect of MPAEA and p-acetamide on cellular toxicity and on silico in HeLa cancer ...
