Browsing by Author "Özoğul, Candan"
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The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats
Kaçamak, Pınar; Özoğul, Candan; Sarıbaş, Gülistan Sanem; Akarca Dizakar, Saadet Özen; Emniyet Sert, Asiye Asli (S. Karger AG, 2020)Objective: Isotretinoin is used in acne vulgaris treatment for more than 20 years. Isotretinoin has serious side effects on many organs, but there are no comprehensive studies investigating its possible toxic effects on ... -
HTK-Alcar, a modified organ transplantation solution, decreases ischemic injury in the rat kidney tissue
Sarıbaş, Gülistan Sanem; Akçay, Neslihan Coşkun; Akyol, Seda Nur; Dayanır, Duygu; Abraheem, Khadeejah; Bilge, Mustafa; Kavutcu, Mustafa; Özoğul, Candan (Gazi Universitesi, 2020)Objectives: Histidine-tryptophan-ketoglutarate (HTK) solution is the storage solution used in organ transplantation. However, such solutions cannot completely eliminate tissue damage. Acetyl L-carnitine (Alcar) is a strong ... -
Investigation of the Protective Effects of Acetyl L-Carnitine on Cisplatin-Induced Uterus Toxicity
Seyhan, Sermin; Sarıbaş, Gulistan Sanem; Akçay, Neslihan Coşkun; Gurgen, Seren Gulsen; Akyol, Seda Nur; Göktaş, Güleser; Hirfanoğlu, Ibrahim Murat; Erdoğan, Deniz; Özoğul, Candan (2018)Objective: The aim of the study was to investigate the prophylactic effects of acetyl L-carnitine against to uterus induced by cisplatin. Methods: Twenty-four female Wistar albino rats were divided into four groups: group ... -
S-allylcysteine inhibits chondrocyte inflammation to reduce human osteoarthritis via targeting RAGE, TLR4, JNK, and Nrf2 signaling: comparison with colchicine
Elmazoglu, Zübeyir; Bek, Zehra Aydin; Sarıbaş, Sanem Gülistan; Özoğul, Candan; Goker, Berna; Bitik, Berivan; Aktekin, Cem Nuri; Karasu, Çimen (Canadıan Scıence Publıshıng, 2021)The discovery of new pharmacological agents is needed to control the progression of osteoarthritis (OA), characterized by joint cartilage damage. Human OA chondrocyte (OAC) cultures were either applied to S-allylcysteine ...