Browsing by Author "Demirel, Nadir"
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Asimetrik aldol tepkimeleri için yeni bir katalizör: Homoboroprolin'in asimetrik katalizör etkisinin modellenmesi
Dülger, Habibe (Ahi Evran Üniversitesi, 2016)Kiral amino boronik asitler, enzim inhibitörleri, anti kanser ajanları moleküler sensörler ve katalizör olarak geniş bir uygulama alanına sahiptirler. Katalizör özellikleri oldukça ilgi çekmektedirler. Yakın zamanda Whiting ... -
Computational Insight Into the Enantioselectivity of Homoboroproline Catalyzed Asymmetric Aldol Reaction
Dulger, Habibe; Sari, Ozlem; Demirel, Nadir; Erdem, Safiye S. (WILEY-V C H VERLAG GMBH, 2019)Chiral amino boronic acids and their derivatives have a wide range of applications including enzyme inhibitors, anti-cancer agents and molecular sensors. They also draw attention as effective catalysts. Recently, a new ... -
Kiral schiff bazları ve Cu (II) komplekslerinin sentezi: DNA bağlanma ve DNA kesme özelliklerinin araştırılması
Kadıoğlu, Rıfkı (Kırşehir Ahi Evran Üniversitesi, 2019)Kiral amino alkollerden elde edilmiş Schiff bazlarının yeni üç adet mononükleer bakır(II) kompleksleri sentezlenmiştir. Bu komplekslerin yapıları element analiz, FTIR/LCMS, manyetik duyarlılık ve molar iletkenlik ölçümleri ... -
pH'a duyarlıi enerji? transfer kasetleri? i?çi?n modül tasarım ve sentezi?
Baydar, Melek (Ahi Evran Üniversitesi, 2015)Bu proje kapsamında pH'a duyarlı piridinetenil ve dimetilaminofeniletenil substitüe bazlı BODİPY modüllerin sentezleri yapılmıştır. 1,4-Fenilen köprüsü ile bağlantılı BODİPY dimerleri arasında enerji transferinin ortamın ... -
Solvent-Free Synthesis of Chiral Schiff-Base Ligands Based on Ferrocene under Microwave Irradiation and Application to Enantioselective Nitroaldol (Henry) Reaction
Ozturk, Gulsen; Colak, Mehmet; Demirel, Nadir (WILEY-BLACKWELL, 2011)Chiral Schiff-bases 3a-f based on ferrocene were designed and synthesized using solvent-free methods by mixing ferrocene carbaldehyde 1 with amino alcohols and amines 2a-f under microwave irradiation and classical method ... -
Synthesis and Antibacterial Activity of New Chiral Aminoalcohol and Benzimidazole Hybrids
Çiçek, İlknur; Tunç, Turgay; Öğütçü, Hatice; Abdurrahmanoglu, Suzan; Günel, Aslıhan; Demirel, Nadir (Wiley-Blackwell, 2020)New chiral aminoalcohol-benzimidazole hybrids have been synthesized from commercially available aminoalcohols. [S(+)-Phenylglycinol, S(−)- Phenylalaninol and S(+)- Leuicinol] and 2-(chloromethyl)-N-tosyl-1-H-benzimidazole. ... -
Synthesis of benzimidazole derivatives containing amide bond and biological evaluation as acetylcholinesterase, carbonic anhydrase I and II inhibitors
Alım, Zuhal; Tunç, Turgay; Demirel, Nadir; Günel, Aslıhan; Karacan, Nurcan (Elsevier B.V., 2022)Acetylcholinesterase (AChE) and carbonic anhydrase I (CA-I) and II (CA-II) are two vital metabolic enzymes. AChE inhibitors are seen as target molecules in drug development studies for Alzheimer's treatment. CA inhibitors ... -
Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: use in the copper-catalyzed enantioselective Henry reaction
Delikus, Rabia; Cakir, Emine; Demirel, Nadir; Balci, Metin; Karatas, Betul (SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAK, 2016)Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetric Henry reaction. Various aromatic aldehydes were converted into chiral beta-nitro alcohols with high yields and moderate ... -
Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: usein the copper-catalyzed enantioselective Henry reaction
Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetricHenry reaction. Various aromatic aldehydes were converted into chiral-nitro alcohols with high yields and moderateto ... -
Three New Copper (II) Complexes with CHIRAL SCHIFF BASES: Synthesis, Characterization, DNA Binding and DNA-Cleavage Studies
Tunc, Turgay; Demirel, Nadir; Emir, Mahmut; Gunel, Ashhan; Kadioglu, Rifki; Karacan, Nurcan (CHEM SOC PAKISTAN, 2019)New mononuclear copper (II) complexes (1, 2 and 3) were synthesized from Schiff bases (H2L) of chiral amino alcohols. The structures of the copper complexes were proposed by a combination of elemental analyses, FTIR, LCMS, ... -
Two-component organogelators: combination of N-epsilon-alkanoyl-L-lysine with various N-alkanoyl-L-amino acids: additional level of hierarchical control
Colak, Mehmet; Baris, Deniz; Evcil, Murat; Demirel, Nadir; Hosgoeren, Halil (TAYLOR & FRANCIS INC, 2018)Synthesis of two-component organogelation system was performed very easy and concise manner from N-epsilon-palmitoyl-L-lysine ethyl ester and N-epsilon-miristoyl-L-lysine ethyl ester in which they were used as base component ... -
Yeni benzimidazol temelli kiral aminoalkollerin sentezi ve antimikrobial etkilerinin araştırılması
Çiçek, İlknur (Kırşehir Ahi Evran Üniversitesi, 2020)Yeni üç adet kiral aminoalkol-benzimidazol hibritleri 4a, 4b ve 4c ticari olarak elde edilen kiral aminoalkoller [S(-)- fenilalaninol, S(+)-fenilglisinol ve S(+)-Leusinol] ile 2-(klorometil)-N-tosil-1-H-benzimidazolün ...
