Browsing by Author "Er, Mustafa"
Now showing items 1-9 of 9
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Novel 2-amino-1,3,4-thiadiazoles and their acyl derivatives: Synthesis, structural characterization, molecular docking studies and comparison of experimental and computational results
Er, Mustafa; Isildak, Gamze; Tahtaci, Hakan; Karakurt, Tuncay (ELSEVIER SCIENCE BV, 2016)This study aims to synthesize and characterize compounds containing 2-amino-1,3,4-thiadiazole and compare experimental results to theoretical results. For this purpose, firstly mono, di and tetra 2-amino-1,3,4-thiadiazole ... -
Novel aldehyde and thiosemicarbazone derivatives: Synthesis, spectroscopic characterization, structural studies and molecular docking studies
Karakurt, Tuncay; Tahtaci, Hakan; Subasi, Nuriye Tuna; Er, Mustafa; Agar, Erbil (ELSEVIER SCIENCE BV, 2016)In this study our purpose is that, synthesis and characterization of compounds containing the aldehyde and thiosemicarbazone groups and comparison of the theoretical results with the experimental results. The structures ... -
Novel substituted benzothiazole and Imidazo[2,1b][1,3,4]Thiadiazole derivatives: Synthesis, characterization, molecular docking study, and investigation of their in vitro antileishmanial and antibacterial activities
Er, Mustafa; Ozer, Arif; Direkel, Sahin; Karakurt, Tuncay; Tahtaci, Hakan (ELSEVIER SCIENCE BV, 2019)In this study, we synthesized new imidazo[2,1-b][1,3,4]thiadiazole derivatives containing benzothiazole group. To this end, we firstly obtained the benzo[d]thiazol-2-ylthio/oxy acetonitrile compounds (3a,b), the starting ... -
Novel Substituted Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives: Synthesis, Characterization, Molecular Docking Study, and Investigation of Their In Vitro Antifungal Activities
Er, Mustafa; Tahtaci, Hakan; Karakurt, Tuncay; Onaran, Abdurrahman (WILEY, 2019)In this study, a new series of substituted imidazo[2,1-b][1,3,4]thiadiazole derivatives were synthesized. To this end, first 2-amino-1,3,4-thiadiazole derivatives (compounds 2a and 2b), the starting materials, were synthesized ... -
A NovelClassSubstitutedImidazo[2,1-b][1,3,4]thiadiazoleDerivatives:Synthesis,Characterization,In VitroBiologicalActivity,andPotentialInhibitorsDesignStudies
Er, Mustafa; Ahmedov, Farid; Karakurt, Tuncay; Direkel, Şahin; Tahtacı, Hakan (Wıley-V Ch Verlag Gmbh, 2019)In this study, imidazo[2,1-b][1,3,4]thiadiazole derivatives were designed and synthesized. All of the synthesized compounds were characterized by H-1 and C-13 nuclear magnetic resonance (H-1 NMR and C-13 NMR), fourier-transform ... -
Synthesis of 1,3,4-thiadiazol-2(3H)-one derivatives via an unexpected intramolecular addition-elimination reaction of 1,3,4-thiadiazoles
Tahtaci, Hakan; Er, Mustafa; Karakurt, Tuncay; Sancak, Kemal (PERGAMON-ELSEVIER SCIENCE LTD, 2017)A new synthesis was developed for 1,3,4-thiadiazol-2(3H)-one derivatives, based on a new arrangement on the thiadiazole ring with an intramolecular addition-elimination reaction. To this end, starting from 5-methyl-1,3,4 ... -
Synthesis, Characterization, Antimicrobial Evaluation, and Computational Investigation of Substituted Imidazo[2,1-b][1,3,4]Thiadiazole Derivatives
Dağlı, Meltem; Er, Mustafa; Karakurt, Tuncay; Onaran, Abdurrahman; Alıcı, Hakan; Tahtaci, Hakan (Wiley-Blackwell, 2020)In this study, a novel series of 2,6-disubstituted and 2,5,6-trisubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives were synthesized starting from 2-amino-1,3,4-thiadiazole derivatives. Structures of the synthesized ... -
Synthesis, characterization, preliminary SAR and molecular docking study of some novel substituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as antifungal agents
Er, Mustafa; Erguven, Bugracan; Tahtaci, Hakan; Onaran, Abdurrahman; Karakurt, Tuncay; Ece, Abdulilah (SPRINGER BIRKHAUSER, 2017)The aim of this study was to synthesize imidazo[2,1-b][1,3,4]thiadiazole derivatives, characterize them with various spectroscopic methods and investigate their antifungal activities. 2-Imino-1,3,4-thiadiazole derivatives ... -
Synthesis, Structural Characterization, and Biological Evaluation of Novel Substituted 1,3-Thiazole Derivatives Containing Schiff Bases
Tahtaci, Hakan; Er, Mustafa; Karakurt, Tuncay; Onaran, Abdurrahman (WILEY, 2017)In this study, thiazole derivatives containing Schiff bases (7-9 a-f) were synthesized in moderate to high yields (49-94%) using the Hantzsch reaction with thiosemicarbazone derivatives (5a-c) and 2bromo- 1-phenylethanone ...
