Browsing by Author "Guclu, Aydin"
Now showing items 1-18 of 18
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The association of profilin-1 levels with survival in chronic kidney disease
Eroglu, Eray; Unal, Hilmi U.; Guclu, Aydin; Kocyigit, Ismail; Karaman, Murat; Saglam, Mutlu; Gezer, Mustafa (WILEY, 2017)BackgroundProfilin-1 is a ubiquitous, actin-binding protein that plays an important role in the regulation of actin polymerization and cytoskeleton remodelling and contributes to vascular dysfunction. We conducted this ... -
A Case of Acute Myocarditis and Rhabdomyolysis after a Scorpion Sting
Ersoy, Suleyman; Yilmaz, Fevzi; Sonmez, Bedriye Muge; Kara, Ali Yucel; Guclu, Aydin (AVES, 2017)Introduction: Scorpion stings continue to be a current public health problem in tropical regions of the world. Local effects are usually seen, but fatal cardiovascular complications may occur, albeit rarely, from scorpion ... -
Catheter-Related Bacteremia in a Hemodialysis Unit: Cronobacter Sakazakii
Sezgin, Fikriye Milletli; Guclu, Aydin; Sevim, Elif; Sevim, Ali (TURK NEFROLOJI DIYALIZ TRANSPLANTASYON DERGISI, 2018)In this study, a case of catheter-related bacteremia caused by Cronobacter sakazakii, which was successfully treated with antibiotic therapy, was presented. Since 1989, cases of contamination of powder infant formula caused ... -
Chitotriosidase as a novel biomarker of early atherosclerosis in hemodialysis patients
Guclu, Aydin; Yilmaz, Mahmut Ilker; Tokmak, Turgut Tursem; Unal, Hilmi Umut; Karaman, Murat; Gezer, Mustafa; Tas, Ahmet (WILEY, 2017)Introduction: Increasing evidence suggests that inflammation and increased macrophage activity have a central role in pathogenesis of atherosclerosis. It is shown that chitotriosidase (CHIT-1) is a marker of macrophage ... -
The effects of grape seed on apoptosis-related gene expression and oxidative stress in streptozotocin-induced diabetic rats
Guclu, Aydin; Yonguc, Nilufer; Dodurga, Yavuz; Gundogdu, Gulsah; Guclu, Zuhal; Yonguc, Tarik; Adiguzel, Esat (TAYLOR & FRANCIS LTD, 2015)Background: Diabetic nephropathy is the most common cause of end-stage renal disease. Emerging evidences indicate that many mechanistic pathways including apoptosis play an important role in the pathogenesis and progression ... -
The effects of ozone therapy on caspase pathways, TNF-alpha, and HIF-1 alpha in diabetic nephropathy
Guclu, Aydin; Erken, Haydar Ali; Erken, Gulten; Dodurga, Yavuz; Yay, Arzu; Ozcoban, Ozge; Simsek, Hasan (SPRINGER, 2016)Accelerated apoptosis plays a vital role in the development of diabetic vascular complications. Ozone may attenuate diabetic nephropathy by means of decreased apoptosis-related genes. The aim of our study was to investigate ... -
IL-33 and ST2 levels in chronic kidney disease: Associations with inflammation, vascular abnormalities, cardiovascular events, and survival
Gungor, Ozkan; Unal, Hilmi Umut; Guclu, Aydin; Gezer, Mustafa; Eyileten, Tayfun; Guzel, Fatma Betul; Altunoren, Orcun (PUBLIC LIBRARY SCIENCE, 2017)Objective Increased inflammation, associated with the increase in chronic kidney disease (CKD) stage, has a very important influence in vascular injury and cardiovascular diseases. In this study, we aimed to investigate ... -
Increased Mean Platelet Volume in Familial Hypercholesterolemia
Icli, Atilla; Aksoy, Fatih; Nar, Gokay; Kaymaz, Haci; Alpay, Mehmet Fatih; Nar, Rukiye; Guclu, Aydin (SAGE PUBLICATIONS INC, 2016)Familial hypercholesterolemia (FH) is a genetic disorder of lipoprotein metabolism and increases the risk of premature cardiovascular diseases. In patients with FH, platelet function may be activated; however, the extent ... -
Micro RNA-320 as a novel potential biomarker in renal ischemia reperfusion
Guclu, Aydin; Kocak, Cengiz; Kocak, Fatma Emel; Akcilar, Raziye; Dodurga, Yavuz; Akcilar, Aydin; Secme, Muecahit (TAYLOR & FRANCIS LTD, 2016)Aim: MicroRNAs (miR) are important diagnostic and treatment targets due to their different tissue expressions and their central position in the regulation of gene expressions. miR studies might pioneer emerging of new ... -
MicroRNA-125b as a new potential biomarker on diagnosis of renal ischemia-reperfusion injury
Guclu, Aydin; Kocak, Cengiz; Kocak, Fatma E.; Akcilar, Raziye; Dodurga, Yavuz; Akcilar, Aydin; Elmas, Levent (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017)Background: Acute renal failure is commonly seen in the perioperative period. Ischemia-reperfusion (IR) injury plays a major role in acute renal failure and delayed graft function. MicroRNAs (miRs), which are pivotal ... -
Nephrotoxic effects of varenicline as the most effective drug used for smoking cessation: a preliminary experimental study
Koc, Akif; Erken, Haydar Ali; Kocak, Fatma Emel; Yay, Arzu; Guclu, Aydin; Sari, Erhan; Simsek, Hasan (SPRINGER, 2015)Varenicline is a new most effective drug for smoking cessation. Its effect on kidney functions remains unclear. This study purposed to investigate whether varenicline causes nephrotoxicity in rats. Fifteen rats were randomly ... -
The Prevalence of Fabry Disease in Patients with Chronic Kidney Disease in Turkey: The TURKFAB Study
Turkmen, Kultigin; Guclu, Aydin; Sahin, Garip; Kocyigit, Ismail; Demirtas, Levent; Erdur, Fatih Mehmet; Sengul, Erkan (KARGER, 2016)Background/Aims: Fabry disease is a treatable cause of chronic kidney disease (CKD) characterized by a genetic deficiency of a-galactosidase A. European Renal Best Practice (ERBP) recommends screening for Fabry disease in ... -
Profilin-1 as a New Potential Biomarker on Diagnosis of Early Atherosclerosis in Hemodialysis Patients
Guclu, Aydin; Sahin, Fuat (EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2017)… -
Relationship between Fragmented QRS Complex and Aortic Stiffness in Chronic Hemodialysis Patients
Guclu, Aydin; Nar, Gokay; Icli, Atilla; Ozhan, Nail; Sezer, Siren (KARGER, 2017)Objective: This study aimed to evaluate the correlation between fragmented QRS complex (fQRS), aortic stiffness, and diastolic dysfunction in hemodialysis patients. Subjects and Methods: A sample of 56 patients who received ... -
The Relationship of Red-Cell Distribution Width and Carotid Intima Media in Chronic Kidney Disease
Guclu, Aydin; Tokmak, Turgut Tursem; Kaymaz, Haci; Turkmen, Kultigin; Senol, Hande; Ozhan, Nail; Dursun, Yusuf (TURK NEFROLOJI DIYALIZ TRANSPLANTASYON DERGISI, 2016)OBJECTIVE: Red-cell distribution width (RDW) is a parameter routinely used for diagnosis of different anemia types. Recent studies have shown the RDW relationship with mortality in general population and patients with ... -
Tp-e/QT and Tp-e/QTc Ratio in Hemodialysis and Peritoneal Dialysis Patients
Guclu, Aydin; Sipahioglu, Murat Hayri; Icli, Atilla; Alpay, Mehmet Fatih; Narman, Serkan (TURK NEFROLOJI DIYALIZ TRANSPLANTASYON DERGISI, 2016)OBJECTIVE: Sudden cardiac death and risk of arrhythmia are higher in patients with ESRD. Tp-e/QT, and Tp-e/QTc are novel and more reliable indexes of ventricular arrhythmogenesis and sudden cardiac death than QTc. The aim ...
