Browsing Yayın Koleksiyonu by Issue Date
Now showing items 1-20 of 51
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Simultaneous Headspace-GC-FID Analysis for Methanol and Ethanol in Blood, Saliva, and Urine: Validation of Method and Comparison of Specimens
(ADVANSTAR COMMUNICATIONS INC, 2010)This study presents a headspace gas chromatography method with flame ionization detection (GC-FID) for the determination of ethanol and methanol content in biological fluids such as blood, urine, and saliva, emphasizing ... -
Effects of the interleukin-6 (IL-6) polymorphism on toxic metal and trace element levels in placental tissues
(ELSEVIER SCIENCE BV, 2011)The placenta is a crucial organ of fetal origin that functions in providing nutrients to the fetus from the mother. During pregnancy, the need for essential micronutrients, such as Fe and Zn, increases due to the requirements ... -
Simultaneous Headspace-GC-FID Analysis for Methanol and Ethanol in Blood, Saliva and Urine: Validation of Method and Comparison of Specimens
(ADVANSTAR COMMUNICATIONS INC, 2011)This study presents a headspace gas chromatography method with flame ionization detection (GC-FID) for the determination of ethanol and methanol content in biological fluids such as blood, urine and saliva, emphasizing ... -
The regulation of microcystin biosynthesis pathways and genetic mechanisms [Mikrosistin biyosentez yolaklari{dotless}ni{dotless}n düzenlenmesi ve genetik mekanizmalar]
(2012)The cyanobacteria (blue-green algae), as they are commonly named, comprise a diverse group of oxygenic photosynthetic bacteria that inhabit a wide range of aquatic and terrestrial environments, and display incredible ... -
Antimicrobial Activity of Bacillus Strains Isolated from Spring Water and A Novel Bacteriocin: RS108
(DR M N KHAN, 2013)The aim of this research was to investigate the bacteriocins produced by Bacillus strains isolated from the spring water of Rize, in Turkey. Bacillus cereus RS108 was identified by both conventional and molecular methods, ... -
Doxorubicin loading, release, and stability of polyamidoamine dendrimer-coated magnetic nanoparticles
(WILEY-BLACKWELL, 2013)Nanotechnology is a promising alternative to overcome the limitations of classical chemotherapy. As a novel approach, dendrimer-coated magnetic nanoparticles (DcMNPs) maintain suitable drug delivery system because of their ... -
Antimicrobial activity of Bacillus strains isolated from spring water and a novel bacteriocin: RS108
(2013)The aim of this research was to investigate the bacteriocins produced by Bacillus strains isolated from the spring water of Rize, in Turkey. Bacillus cereus RS108 was identified by both conventional and molecular methods, ... -
PAMAM dendrimer-coated iron oxide nanoparticles: synthesis and characterization of different generations
(SPRINGER, 2013)This study focuses on the synthesis and characterization of different generations (G(0)-G(7)) of polyamidoamine (PAMAM) dendrimer-coated magnetic nanoparticles (DcMNPs). In this study, superparamagnetic iron oxide nanoparticles ... -
Polyinosinic: polycytidylic acid loading onto different generations of PAMAM dendrimer-coated magnetic nanoparticles
(SPRINGER, 2013)Poly (I:C), which is a synthetic double-stranded RNA, have significant toxicity on tumor cells. The immobilization of Poly (I:C) onto nanoparticles is important for the fabrication of targeted delivery systems. In this ... -
Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2014)The ends of chromosoms, telomeres are bound with a number of proteins which protect and stabilize telomeres against degredation, end to end fusion and aberrant recombinations. Telomeric DNA is bound of two groups of proteins, ... -
Polyhydroxybutyrate-Coated Magnetic Nanoparticles for Doxorubicin Delivery: Cytotoxic Effect Against Doxorubicin-Resistant Breast Cancer Cell Line
(LIPPINCOTT WILLIAMS & WILKINS, 2014)In this study, polyhydroxybutyrate (PHB)-coated magnetic nanoparticles (MNPs) were prepared by coprecipitation of iron salts (Fe2+ and Fe3+) by ammonium hydroxide. Characterizations of PHB-coated MNPs were performed by ... -
Idarubicin-loaded folic acid conjugated magnetic nanoparticles as a targetable drug delivery system for breast cancer
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2014)Conventional cancer chemotherapies cannot differentiate between healthy and cancer cells, and lead to severe side effects and systemic toxicity. Another major problem is the drug resistance development before or during the ... -
Chitosan magnetic nanoparticles for pH responsive Bortezomib release in cancer therapy
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2014)The use of nanotechnology in cancer treatment offers exciting opportunities, including the possibility of destroying tumors with minimal damage to healthy tissue by novel targeted drug delivery systems. pH differences ... -
Association of -174G/C interleukin-6 gene polymorphism with the risk of chronic lymphocytic, chronic myelogenous and acute myelogenous leukemias in Turkish patients
(Zerbinis Publications, 2014)Purpose: The purpose of this study was to evaluate the relationship between -174G/C interleukin-6 (IL-6) gene promoter polymorphism and susceptibility to chronic lymphocytic (CLL), chronic myelogenous (CML) and acute ... -
Association of-174G/C interleukin-6 gene polymorphism with the risk of chronic lymphocytic, chronic myelogenous and acute myelogenous leukemias in Turkish patients
(ZERBINIS MEDICAL PUBL, 2014)Purpose: The purpose of this study was to evaluate the relationship between -174G/C interleukin-6 (IL-6) gene promoter polymorphism and susceptibility to chronic lymphocytic (CLL), chronic myelogenous (CML) and acute ... -
Synthesis of Doxorubicin loaded magnetic chitosan nanoparticles for pH responsive targeted drug delivery
(ELSEVIER SCIENCE BV, 2014)Targeted drug delivery is a promising alternative to overcome the limitations of classical chemotherapy. In an ideal targeted drug delivery system carrier nanoparticles would be directed to the tumor tissue and selectively ... -
Effect of gemcitabine and retinoic acid loaded PAMAM dendrimer-coated magnetic nanoparticles on pancreatic cancer and stellate cell lines
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2014)Gemcitabine is an anticancer drug used in the treatment of different cancer types, including pancreatic ductal adenocarcinoma. The maximum tolerated dose in humans is restricted by its side effects on healty cells. ... -
DNA repair gene XRCC1 and XRCC3 polymorphisms and their association with chronic myelogenous leukemia
(Gesdav, 2014)Objective: In this study, due to its importance in DNA repair in cancer, we searched for polymorphisms of XRCC1 and XRCC3 genes in Turkish chronic myelogenous leukemia (CML) patients. Materials and Methods: In order to ... -
Association between XRCC3 Thr241Met polymorphism and laryngeal cancer susceptibility in Turkish population
(SPRINGER, 2015)DNA repair systems are essential for normal cell function. Genetic alterations in the DNA repair genes such as X-ray repair cross-complementing group 3 (XRCC3), can cause a change in protein activity which results in cancer ... -
Study on physiochemical structure and in vitro release behaviors of doxycycline-loaded PCL microspheres
(WILEY-BLACKWELL, 2015)This study aimed to develop drug delivery system of doxycycline-loaded polycaprolactone (PCL) microspheres. The investigated microsphere formulation can be considered for local application in bone infections and degenerative ...
