Yayın Koleksiyonu
Recent Submissions
-
Hepatoprotective actions of melatonin by mainly modulating oxidative status and apoptosis rate in lipopolysaccharide-induced liver damage
(Taylor and Francis Ltd., 2023)Aim: One of the serious complications of sepsis is liver damage and liver failure. This study aimed to evaluate the protective and therapeutic potential of melatonin in rats with lipopolysaccharide-induced sepsis. Main ... -
S-allylcysteine inhibits chondrocyte inflammation to reduce human osteoarthritis via targeting RAGE, TLR4, JNK, and Nrf2 signaling: comparison with colchicine
(Canadıan Scıence Publıshıng, 2021)The discovery of new pharmacological agents is needed to control the progression of osteoarthritis (OA), characterized by joint cartilage damage. Human OA chondrocyte (OAC) cultures were either applied to S-allylcysteine ... -
The effect of astaxanthin on amiodarone induced cardiac tissue damage in rat
(Çukurova Uni, 2023)Purpose: The aim of this study was to evaluate the effect of astaxanthin on amiodarone induced cardiac tissue damage.Materials and Methods: 3 groups were formed using 30 Wistar albino rats. In group 1 (control group) (n=10), ... -
Ellagic Acid Inhibits TGFβ1/Smad-Induced Renal Fibrosis in Diabetic Kidney Injury
(Duzce University Medical School, 2022)Aim: Free radical formation increases due to hyperglycemia occurring in the pathogenesis of diabetes mellitus (DM), and as a result, oxidative stress occurs. Hyperglycemia-mediated oxidative stress plays an important role ... -
Protective effect of resveratrol on cisplatin induced damage in rat kidney
(Çukurova Uni, 2022)Purpose: The aim of this study was to evaluate the protective effect of resveratrol on cisplatin induced damage in rat kidney. Materials and Methods: 30 female Wistar-Albino rats were allocated to form three groups: In ... -
HTK-Alcar, a modified organ transplantation solution, decreases ischemic injury in the rat kidney tissue
(Gazi Universitesi, 2020)Objectives: Histidine-tryptophan-ketoglutarate (HTK) solution is the storage solution used in organ transplantation. However, such solutions cannot completely eliminate tissue damage. Acetyl L-carnitine (Alcar) is a strong ... -
The Protective Effect of Resveratrol on Cisplatin Induced Damage in Rat Liver
(Galenos Publishing House, 2022)Aim: One of the underlying causes of cisplatin-induced hepatotoxicity is oxidative stress. We assessed the effect of an antioxidant, resveratrol, on cisplatin-induced damage in the rat liver. Methods: The project-starting ... -
The Effect of Isotretinoin on Oocyte Maturation in Adolescent Female Rats
(S. Karger AG, 2020)Objective: Isotretinoin is used in acne vulgaris treatment for more than 20 years. Isotretinoin has serious side effects on many organs, but there are no comprehensive studies investigating its possible toxic effects on ... -
A Comparison of Ramipril and Bevacizumab to Mitigate Radiation-Induced Brain Necrosis: An Experimental Study
(Elsevier Inc., 2020)Background: Bevacizumab, an anti-vascular endothelial growth factor (VEGF) antibody, is a new treatment approach for radionecrosis. In our study, we compared the prophylactic and therapeutic usage of a promising agent, ... -
The impact of granulocyte colony-stimulating factor (G-CSF) on thin endometrium of an animal model with rats
(Taylor and Francis Ltd., 2021)Purpose: To evaluate whether G-CSF improves the endometrial thickness of thin endometrium by influencing proliferative, angiogenic and apoptotic factors, an experimental rat model was conducted using 24 female adult rats ... -
Protective effect of edaravone on cisplatin-induced injury in rat ovary
(Springer Science and Business Media Deutschland GmbH, 2022)Purpose: This study was aimed to evaluate the protective effect of edaravone on cisplatin-induced ovarian injury. Methods: A total 40 female Wistar–Albino rats were utilized to form four groups: Group 1 (control group) (n ... -
The Effect of Decompression on The Treatment of Chronic Constriction Injury in Peripheral Nerve
(KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2016)Chronic constriction injury (CCI) is a common clinical entity and characterized by allodynia or spontaneous neuropathic pain. Treatment of neuropathic pain is difficult, because a lack of knowledge about the underlying ... -
The effect of sperm activation on pinopod formation in endometrial epithelium
(ELSEVIER SCIENCE BV, 2016)Introduction: Endometrial receptivity is crucial in implantation of the developing embryo in the endometrium and formation of the pregnancy. In this study, possible effect of sperm and uterine endometrial contact on formation ... -
Can a Small Intestine Segment Be an Alternative Biological Conduit for Peripheral Nerve Regeneration?
(GALENOS YAYINCILIK, 2017)Background: Autologous nerve grafts are used to bridge peripheral nerve defects. Limited sources and donor site morbidity are the major problems with peripheral nerve grafts. Although various types of autologous grafts ... -
Investigation of the Protective Effects of Acetyl L-Carnitine on Cisplatin-Induced Uterus Toxicity
(GAZI UNIV, FAC MED, 2018)Objective: The aim of the study was to investigate the prophylactic effects of acetyl L-carnitine against to uterus induced by cisplatin. Methods: Twenty-four female Wistar albino rats were divided into four groups: group ... -
Nerve Tissue Prefabrication Inside the Rat Femoral Bone: Does It Work?
(TURKISH NEUROSURGICAL SOC, 2017)AIM: To investigate whether nerve regeneration can be induced in the tubular bone between distal and proximal cut nerve ends. MATERIAL and METHODS: Twenty adult Wistar rats were used for the study. Rats were divided into ... -
The effects of iloprost and alprostadil on ischemia-reperfusion injury in preventing inflammation, tissue degeneration, and apoptosis in rat skeletal muscle
(TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEY, 2017)Background/aim: The protective effects of prostaglandin (PG) analogs on ischemia-reperfusion (I/R) have been well documented; however, comparative studies are lacking. The aim of the present study was to determine whether ... -
Determination of the effects of bone marrow derived mesenchymal stem cells and ovarian stromal stem cells on follicular maturation in cyclophosphamide induced ovarian failure in rats
(ELSEVIER TAIWAN, 2019)Objective: Chemotherapy causes depletion of primordial follicles that leads to premature ovarian failure in female cancer survivals. We investigated the effect of bone marrow derived mesenchymal (BMMSCs) and ovarian stromal ... -
Comparison of Efficacy and Safety of Two Tea Tree Oil-Based Formulations in Patients with Chronic Blepharitis: A Double-Blinded Randomized Clinical Trial
Introduction: It was aimed to evaluate the efficacy of two tea tree oil (TTO)-based cleansing gels in chronic blepharitis patients. Methods: Group-1 (basic gel containing 3%(w/w)-TTO) included 50 eyes of 25 patients and ...