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dc.contributor.authorGuleli, Muge
dc.contributor.authorErdem, Safiye S.
dc.contributor.authorOcal, Nuket
dc.contributor.authorErden, Ihsan
dc.contributor.authorSari, Ozlem
dc.date.accessioned2019-11-24T20:38:11Z
dc.date.available2019-11-24T20:38:11Z
dc.date.issued2019
dc.identifier.issn0922-6168
dc.identifier.issn1568-5675
dc.identifier.urihttps://dx.doi.org/10.1007/s11164-018-03721-z
dc.identifier.urihttps://hdl.handle.net/20.500.12513/2484
dc.descriptionWOS: 000461305200025en_US
dc.description.abstractAn efficient and general method for the synthesis of substituted 3,4-dimethylisoxazolo[5,4-b]pyridine-5-carboxamide and benzo[b][1,8]naphthyridine-3-carboxamide derivatives by using 2,2,6-trimethyl-4H-1,3-dioxin-4-one, benzyl amine, aromatic aldehydes, 2-aminoquinoline, or 5-amino-3-methylisoxazole in the presence of a catalytic amount of p-toluenesulfonic acid or iodine is described. The formation of the products was investigated and the results obtained were also supported by theoretical calculations.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [112T880]; National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [SC1GM082340]en_US
dc.description.sponsorshipN. Ocal gratefully acknowledges financial support of this work by the Scientific and Technological Research Council of Turkey (TUBITAK, project no. 112T880). I. Erden acknowledges financial support of this work by funds from the National Institutes of Health (grant no. SC1GM082340). The numerical calculations reported in this paper were partially performed at TUBITAK ULAKBIM, High Performance and Grid Computing Center (TRUBA resources).en_US
dc.language.isoengen_US
dc.publisherSPRINGERen_US
dc.relation.isversionof10.1007/s11164-018-03721-zen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIsoxazolesen_US
dc.subject1,8-Naphthyridinesen_US
dc.subjectCatalysten_US
dc.subjectConjugated heterocyclesen_US
dc.subjectComputational studiesen_US
dc.titleA three-component, one-pot synthesis of 1,8-naphthyridine and isoxazole derivatives and computational elucidation of the mechanismen_US
dc.typearticleen_US
dc.relation.journalRESEARCH ON CHEMICAL INTERMEDIATESen_US
dc.contributor.departmentKırşehir Ahi Evran Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümüen_US
dc.identifier.volume45en_US
dc.identifier.issue4en_US
dc.identifier.startpage2119en_US
dc.identifier.endpage2134en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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