| dc.contributor.author | Sardan, Melis | |
| dc.contributor.author | Sezer, Serdar | |
| dc.contributor.author | Gunel, Aslihan | |
| dc.contributor.author | Akkaya, Mahinur | |
| dc.contributor.author | Tanyeli, Cihangir | |
| dc.date.accessioned | 2019-11-24T20:38:45Z | |
| dc.date.available | 2019-11-24T20:38:45Z | |
| dc.date.issued | 2012 | |
| dc.identifier.issn | 0960-894X | |
| dc.identifier.uri | https://dx.doi.org/10.1016/j.bmcl.2012.07.090 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12513/2572 | |
| dc.description | WOS: 000308046800010 | en_US |
| dc.description | PubMed ID: 22902655 | en_US |
| dc.description.abstract | An efficient synthesis of racemic and both enantiomeric forms of heteroaryl substituted gamma- and delta-lactone derivatives derived from allyl and homoallyl alcohol backbones has been accomplished via ring closing metathesis reaction. 2-Heteroaryl substituted allyl and homoallyl alcohols have been efficiently resolved through enzymatic method with high ee (97-99%) and known stereochemistry. Antimicrobial and antioxidant activities of target lactones were evaluated. (C) 2012 Elsevier Ltd. All rights reserved. | en_US |
| dc.description.sponsorship | Turkish Scientific and Technical Research CouncilTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-108T072] | en_US |
| dc.description.sponsorship | We are grateful to the Turkish Scientific and Technical Research Council for a Grant (No. TBAG-108T072). We thank Nese Ozgazi and Umran Aydemir Sezer for their help in antimicrobial tests. | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | en_US |
| dc.relation.isversionof | 10.1016/j.bmcl.2012.07.090 | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Asymmetric synthesis | en_US |
| dc.subject | Enzymatic resolution | en_US |
| dc.subject | Optically active lactones | en_US |
| dc.title | Synthesis and biological evaluation of optically active conjugated gamma- and delta-lactone derivatives | en_US |
| dc.type | article | en_US |
| dc.relation.journal | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | en_US |
| dc.contributor.department | Kırşehir Ahi Evran Üniversitesi, Fen-Edebiyat Fakültesi, Kimya Bölümü | en_US |
| dc.identifier.volume | 22 | en_US |
| dc.identifier.issue | 18 | en_US |
| dc.identifier.startpage | 5814 | en_US |
| dc.identifier.endpage | 5818 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
