| dc.contributor.author | Ozel B. | |
| dc.contributor.author | Aydin O. | |
| dc.contributor.author | Oztop M.H. | |
| dc.date.accessioned | 2019-11-24T20:59:06Z | |
| dc.date.available | 2019-11-24T20:59:06Z | |
| dc.date.issued | 2019 | |
| dc.identifier.issn | 0144-8617 | |
| dc.identifier.uri | https://dx.doi.org/10.1016/j.carbpol.2019.115469 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12513/3217 | |
| dc.description.abstract | Hydrogels are great systems for bioactive agent encapsulation and delivery. In this study, polysaccharide blended whey protein isolate (WPI) based hydrogels were loaded with black carrot (Daucus carota) concentrate (BC) and in vitro gastrointestinal release measurements were performed. Prior to 6 h digestion in simulated intestinal fluid (SIF), all hydrogels were exposed to simulated gastric fluid (SGF) for 2 h. Pectin (PC), gum tragacanth (GT) and xanthan gum (XG) were the polysaccharides used with WPI to manipulate the release behavior. Physico-chemical changes of the hydrogels throughout the digestion were evaluated by Fourier transform infrared (FTIR) spectroscopy and nuclear magnetic resonance (NMR) relaxometry measurements. Each polysaccharide induced different physico-chemical interactions within the hydrogels due to their distinct structural characteristics. Polysaccharide blending to hydrogels also retarded the release rates in all samples in SIF (p < 0.05). Moreover, microstructural differences between hydrogels were evaluated by scanning electron microscope (SEM) images. © 2019 Elsevier Ltd | en_US |
| dc.description.sponsorship | Orta Doğu Teknik Üniversitesi: DKT-314-2018-3596 --We would like to thank Ulku Ertugrul and Berkay Bolat for their contribution to the study. We also would like to acknowledge COST Action CA 15209 EURELAX - European Network on NMR Relaxometry since some of the findings were discussed in the action’s network meetings. A part of the funding also came from Dr. Oztop’s award of Science Academy’s Young Scientist Awards Program (BAGEP) and Middle East Technical University research funds with grant # DKT-314-2018-3596 . Appendix A -- | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Elsevier Ltd | en_US |
| dc.relation.isversionof | 10.1016/j.carbpol.2019.115469 | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Digestion | en_US |
| dc.subject | FTIR | en_US |
| dc.subject | Hydrogel | en_US |
| dc.subject | NMR | en_US |
| dc.subject | Release | en_US |
| dc.subject | SEM | en_US |
| dc.subject | Whey protein | en_US |
| dc.title | In vitro digestion of polysaccharide including whey protein isolate hydrogels | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Carbohydrate Polymers | en_US |
| dc.contributor.department | Kırşehir Ahi Evran Üniversitesi, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
