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MicroRNA-125b as a new potential biomarker on diagnosis of renal ischemia-reperfusion injury

Guclu, Aydin; Kocak, Cengiz; Kocak, Fatma E.; Akcilar, Raziye; Dodurga, Yavuz; Akcilar, Aydin; Elmas, Levent (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2017)

Background: Acute renal failure is commonly seen in the perioperative period. Ischemia-reperfusion (IR) injury plays a major role in acute renal failure and delayed graft function. MicroRNAs (miRs), which are pivotal ...

The effects of ozone therapy on caspase pathways, TNF-alpha, and HIF-1 alpha in diabetic nephropathy

Guclu, Aydin; Erken, Haydar Ali; Erken, Gulten; Dodurga, Yavuz; Yay, Arzu; Ozcoban, Ozge; Simsek, Hasan (SPRINGER, 2016)

Accelerated apoptosis plays a vital role in the development of diabetic vascular complications. Ozone may attenuate diabetic nephropathy by means of decreased apoptosis-related genes. The aim of our study was to investigate ...

Micro RNA-320 as a novel potential biomarker in renal ischemia reperfusion

Guclu, Aydin; Kocak, Cengiz; Kocak, Fatma Emel; Akcilar, Raziye; Dodurga, Yavuz; Akcilar, Aydin; Secme, Muecahit (TAYLOR & FRANCIS LTD, 2016)

Aim: MicroRNAs (miR) are important diagnostic and treatment targets due to their different tissue expressions and their central position in the regulation of gene expressions. miR studies might pioneer emerging of new ...

The effects of grape seed on apoptosis-related gene expression and oxidative stress in streptozotocin-induced diabetic rats

Guclu, Aydin; Yonguc, Nilufer; Dodurga, Yavuz; Gundogdu, Gulsah; Guclu, Zuhal; Yonguc, Tarik; Adiguzel, Esat (TAYLOR & FRANCIS LTD, 2015)

Background: Diabetic nephropathy is the most common cause of end-stage renal disease. Emerging evidences indicate that many mechanistic pathways including apoptosis play an important role in the pathogenesis and progression ...