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dc.contributor.authorKemeriz, Funda
dc.contributor.authorTuncer, Sibel Çiğdem
dc.contributor.authorAcar, Emine Müge
dc.contributor.authorTuğrul, Burcu
dc.date.accessioned2022-11-11T08:06:37Z
dc.date.available2022-11-11T08:06:37Z
dc.date.issued2020en_US
dc.identifier.citationKemeriz, F., Tuncer, S. Ç., Acar, E. M., & Tuğrul, B. (2020). Evaluation of 25‐hydroxy vitamin D levels and disease severity in patients with acne vulgaris. Dermatologic Therapy, 33(3), e13393.en_US
dc.identifier.issn13960296
dc.identifier.urihttps://doi.org/10.1111/dth.13393
dc.identifier.urihttps://hdl.handle.net/20.500.12513/4724
dc.description.abstractAcne vulgaris is a multifactorial skin disorder. Many etiological factors are speculated to contribute to the pathogenesis of acne, one of these is vitamin D deficiency. Previous studies reported contradictory results about serum 25 hydroxy vitamin D (25-OH vitamin D) levels, its association with acne, some claimed that acne lesion might improve with vitamin D supplementation. We aimed to assess serum 25-OH vitamin D levels in acne patients, identify their relation with disease severity in a larger study group. The study included 134 acne patients, 129 controls. Acne disease severity was identified with Global Acne Grading Scale (GAGS) scores. Serum 25-OH vitamin D levels were measured in all groups. Serum 25-OH vitamin D levels were significantly lower in acne patients than in controls (P <.001). The prevalence of vitamin D deficiency was significantly higher in acne group than in control group (77.6% vs 63.9%; P =.041). There was a negative-strong statistically significant correlation detected between serum 25-OH vitamin D levels and GAGS scores in patient group (P <.001; r = −.910). According to these results, we claim that evaluating serum 25-OH vitamin D levels in acne patients, vitamin D supplementation as a treatment option may be a consideration for further studies. © 2020 Wiley Periodicals LLC.en_US
dc.language.isoengen_US
dc.publisherBlackwell Publishing Inc.en_US
dc.relation.isversionof10.1111/dth.13393en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectacneen_US
dc.subjectdisease severityen_US
dc.subjectvitamin Den_US
dc.titleEvaluation of 25-hydroxy vitamin D levels and disease severityin patients with acne vulgarisen_US
dc.typearticleen_US
dc.relation.journalDermatologic Therapyen_US
dc.contributor.departmentTıp Fakültesien_US
dc.contributor.authorIDEmine Müge Acar / 0000-0001-9592-5599en_US
dc.identifier.volume33en_US
dc.identifier.issue3en_US
dc.identifier.startpage1en_US
dc.identifier.endpage4en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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