Gelişmiş Arama

Basit öğe kaydını göster

dc.contributor.authorSahin, Burc E.
dc.contributor.authorÇelikbilek, Asuman
dc.contributor.authorKoçak, Yusuf
dc.contributor.authorİlanbey, Bilal
dc.contributor.authorSaltoğlu, Gamze T.
dc.contributor.authorKonar, Naime M.
dc.contributor.authorHızmalı, Lokman
dc.date.accessioned2023-03-14T12:55:58Z
dc.date.available2023-03-14T12:55:58Z
dc.date.issued2023en_US
dc.identifier.citationSahin, B. E., Celikbilek, A., Kocak, Y., Ilanbey, B., Saltoglu, G. T., Konar, N. M., & Hizmali, L. (2023). Neurological symptoms and neuronal damage markers in acute COVID‐19: Is there a correlation? A pilot study. Journal of Medical Virology, 95(1), e28240.en_US
dc.identifier.issn0146-6615
dc.identifier.urihttps://doi.org/10.1002/jmv.28240
dc.identifier.urihttps://hdl.handle.net/20.500.12513/4967
dc.description.abstractA wide spectrum of neurological symptoms (NS) has been described in patients with COVID-19. We examined the plasma levels of neuron-specific enolase (NSE) and neurofilament light chain (NFL) together, as neuronal damage markers, and their relationships with clinical severity in patients with NS at acute COVID-19. A total of 20 healthy controls and 59 patients with confirmed COVID-19 were enrolled in this pilot prospective study. Serum NSE and NFL levels were measured by using the enzyme-linked immunoassay method from serum samples. Serum NSE levels were found to be significantly higher in the severe group than in the nonsevere group (p = 0.034). However, serum NFL levels were similar between the control and disease groups (p > 0.05). For the mild group, serum NFL levels were significantly higher in patients with the sampling time >= 5 days than in those with the sampling time <5 days (p = 0.019). However, no significant results for NSE and NFL were obtained in patients with either single or multiple NS across the groups (p > 0.05). Increased serum NSE levels were associated with disease severity regardless of accompanied NS in patients with acute COVID-19 infection. However, serum NFL levels may have a role at the subacute phase of COVID-19.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.isversionof10.1002/jmv.28240en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjectneurofilament light chainen_US
dc.subjectneurological symptomsen_US
dc.subjectneuron-specific enolaseen_US
dc.subjectneuronal damageen_US
dc.titleNeurological symptoms and neuronal damage markers in acute COVID-19: Is there a correlation? A pilot studyen_US
dc.typearticleen_US
dc.relation.journalJournal Of Medıcal Vırologyen_US
dc.contributor.departmentTıp Fakültesien_US
dc.contributor.authorIDBurç Esra Şahin/ 0000-0003-1008-2743en_US
dc.contributor.authorIDAsuman Çelikbilek / 0000-0002-2367-1128en_US
dc.contributor.authorIDYusuf Koçak / 0000-0003-4511-1321en_US
dc.contributor.authorIDBilal İlanbey / 0000-0002-7614-281Xen_US
dc.contributor.authorIDNaime Meriç Konar / 0000-0002-6593-7617en_US
dc.contributor.authorIDLokman Hızmalı / 0000-0001-9548-3030en_US
dc.identifier.volume95en_US
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.endpage7en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster