A Case of Primary Undifferenti- ated Pleomorphic Sarcoma of the Lung

Abstract

Sir, Undifferentiated sarcomas comprise upto 20% of all sarcomas. Malignant fibrous histiocytoma (MFH) and its subtypes have been finally removed from the WHO 2013 classification.1,2 Many tumors previously classified as MFH have been reclassified as “undifferentiated pleomorphic sarcomas" (UPSs).3 UPS is extremely rare among the primary tumors of the lung (<0.5% of all lung cancers) and is essentially a diagnosis of exclusion. Primary UPS of the lung was previously reported in approximately 85 cases in literature.4 Two-hundred cases of soft tissue MFH were presented first by Weiss and Enzinger in 1978.5 After one year, Bedrossian et al. described the first case of primary pulmonary MFH.6