| dc.contributor.author | Özden, Hüseyin | |
| dc.contributor.author | Şahin, Yaşar | |
| dc.contributor.author | Kilitçi, Asuman | |
| dc.contributor.author | Karaca, Gökhan | |
| dc.contributor.author | Gömeç, Muhammed | |
| dc.contributor.author | Yıldız, Ahmet | |
| dc.contributor.author | Uçar, Cahit | |
| dc.date.accessioned | 2023-08-09T11:57:36Z | |
| dc.date.available | 2023-08-09T11:57:36Z | |
| dc.date.issued | 2022 | en_US |
| dc.identifier.citation | Özden, H., Şahin, Y., Kilitçi, A., Karaca, G., Gömeç, M., Yildiz, A., & Uçar, C. (2022). Comparison of the healing effects of mesazaline and Ganoderma lucidum in acetic acid-induced colitis in rats. Annals of Surgical Treatment and Research, 102(1), 29-35. | en_US |
| dc.identifier.issn | 22886575 | |
| dc.identifier.uri | https://doi.org/10.4174/ASTR.2022.102.1.29 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12513/5285 | |
| dc.description.abstract | Purpose: The etiology and pathogenesis of distal colitis (DC) are poorly understood. Activation of intestinal inflammatory response may lead to intestinal tissue necrosis. Antioxidant and anti-inflammatory agents are among the treatment options. Our study aimed to compare the protective effects of mesalazine and Ganoderma lucidum in acetic acid (AA)induced colitis in rats. Methods: Twenty-four rats were randomly grouped as colitis, mesalazine, G. lucidum, and combined (G. lucidum + mesalazine) groups. DC was induced by intrarectal administration of AA. Statistical comparisons were done by using parameters including colonic tissue IL-1, IL-6, TNF-α, and CRP levels. Histopathologic changes of the samples of colonic tissue were scored as mucosal damage score and inflammatory score. A P-value of [removed] | en_US |
| dc.language.iso | eng | en_US |
| dc.publisher | Korean Surgical Society | en_US |
| dc.relation.isversionof | 10.4174/ASTR.2022.102.1.29 | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Acetic acid | en_US |
| dc.subject | Distal colitis | en_US |
| dc.subject | Ganoderma lucidum | en_US |
| dc.subject | Mesalazine | en_US |
| dc.title | Comparison of the healing effects of mesazaline and Ganoderma lucidum in acetic acid-induced colitis in rats | en_US |
| dc.type | article | en_US |
| dc.relation.journal | Annals of Surgical Treatment and Research | en_US |
| dc.contributor.department | Tıp Fakültesi | en_US |
| dc.contributor.authorID | Asuman Kilitçi / 0000-0002-5489-2222 | en_US |
| dc.contributor.authorID | Cahit Uçar / 0000-0002-3386-0301 | en_US |
| dc.identifier.volume | 102 | en_US |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.startpage | 29 | en_US |
| dc.identifier.endpage | 35 | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
