Synthesis of novel chiral bisoxazoline ligands with a norbornadiene backbone: usein the copper-catalyzed enantioselective Henry reaction
Özet
Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetricHenry reaction. Various aromatic aldehydes were converted into chiral-nitro alcohols with high yields and moderateto acceptable enantioselectivities under the optimized reaction conditions. Novel chiral bisoxazoline ligands based on norbornadiene were synthesized and used for the asymmetricHenry reaction. Various aromatic aldehydes were converted into chiral-nitro alcohols with high yields and moderateto acceptable enantioselectivities under the optimized reaction conditions.