Yazar "Karacan, Nurcan" için listeleme
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Acetohydroxyacid Synthase (AHAS) Inhibitor-Based Commercial Sulfonylurea Herbicides as Glutathione Reductase Inhibitors: in Vitro and in Silico Studies
Sel, Sedat; Tunç, Turgay; Ortaakarsu, Ahmet Buğra; Mamaş, Serhat; Karacan, Nurcan; Karacan, Mehmet Sayım (John Wiley and Sons Inc, 2022)In this study, in vitro inhibitory effect of AHAS inhibiting-based commercial sulfonylurea herbicides on human GR and S. cerevisiae GR was determined by electrochemical method. Our findings, the first report in literature, ... -
Antimony(III) complexes with 2-amino-4,6-dimethoxypyrimidines: Synthesis, characterization and biological evaluation
Tunc, Turgay; Karacan, Mehmet Sayim; Ertabaklar, Hatice; Sari, Musa; Karacan, Nurcan; Buyukgungor, Orhan (ELSEVIER SCIENCE SA, 2015)Novel pyrimidine compound bearing disulfide bridge, 5,5'-disulfanediyIbis(2-amino-4,6-dimetoxypyrimidine) (3) was synthesized by reduction of 2-amino-4,6-dimethoxy-5-thiocyanatopyrimidine for the first time, and its structure ... -
Conformational analysis, vibrational and NMR spectroscopic study of the methanesulfonamide-N,N '-1,2-ethanediylbis
Alyar, Hamit; Unal, Arslan; Ozbek, Neslihan; Alyar, Saliha; Karacan, Nurcan (PERGAMON-ELSEVIER SCIENCE LTD, 2012)A conformational analysis of the methanesulfonamide-N,N'-1,2-ethanediylbis (msen) was performed by using vibrational and NMR spectroscopies as well as theoretical computations. The possible stable conformers of msen on its ... -
DNA cleavage, antimicrobial studies and a DFT-based QSAR study of new antimony(III) complexes as glutathione reductase inhibitor
Tunc, Turgay; Koc, Yasemin; Acik, Leyla; Karacan, Mehmet Sayim; Karacan, Nurcan (PERGAMON-ELSEVIER SCIENCE LTD, 2015)New antimony(III) complexes, [Sb(2-aminopyridine)(2)Cl-3]), (1a), [Sn(2-aminopyridine)(2)Br-3] (1b), [Sb(5-methyl-2-aminopyridine)(2)Cl-3] (2a), [Sb(5-methyl-2-aminopyridine)(2)Br-3] (2b), [Sb(2-aminopyrimidine)(2)Cl-3] ... -
Experimental and theoretical studies on methanesulfonic acid 1-methylhydrazide: Antimicrobial activities of its sulfonyl hydrazone derivatives
Ozbek, Neslihan; Alyar, Saliha; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2009)Methanesulfonic acid 1-methylhydrazide (msmh) and its sulfonyl hydrazone derivatives, salicylaldehyde-N-methylmethanesulfonylhydrazone (salmsmh) and 2-hydroxy-1-naphthaldehyde-N-methylmethanesulfonylhydrazone (nafmsmh) ... -
A new method for screening glutathione reductase inhibitors using square wave voltammetry
Karacan, Mehmet Sayim; Tunc, Turgay; Oruc, Hatice; Mamas, Serhat; Karacan, Nurcan (ROYAL SOC CHEMISTRY, 2015)A square wave voltammetric method was developed for the detection of glutathione reductase (GR) activity. The method is based upon the direct determination of glutathione (GSH) produced by nicotinamide adenine dinucleotide ... -
New Schiff bases with a 2,6-bis(2-aminophenylthio)pyridine moiety acting as glutathione reductase activator and inhibitors: Synthesis and molecular docking studies
Tunç, Turgay; Ortaakarsu, Ahmet Buğra; Hatipoğlu, Seda Muhsir; Kazancı, Uğur; Karaböcek, Serdar; Dege, Necmi; Karacan, Nurcan (Elsevier B.V., 2022)2,6-bis(2-aminophenylthio)pyridine was synthesized and identified by x-ray diffraction method. Its new Schiff bases (H2L1, H2L2, L3 and L4) were synthesized and characterized by elemental analysis, FT-IR, LC-MS, 1H NMR and ... -
New Schiffbases with a 2,6-bis(2-aminophenylthio)pyridine moiety acting as glutathione reductase activator and inhibitors: Synthesis and molecular docking studies
Tunç, Turgay; Ortaakarsu, Ahmet Buğra; Hatipoğlu, Seda Muhsir; Kazancı, Uğur; Karaböcek, Serdar; Karaböcek, Nevin; Dege, Necmi; Karacan, Nurcan (Elsevier, 2022)2,6-bis(2-aminophenylthio)pyridine was synthesized and identified by x-ray diffraction method. Its new Schiffbases (H2L1, H2L2, L-3 and L-4) were synthesized and characterized by elemental analysis, FT-IR, LC-MS, H-1 NMR ... -
Quantitative structure-activity relationships studies for prediction of antimicrobial activity of synthesized disulfonamide derivatives
Alyar, Saliha; Ozbek, Neslihan; Kuzukiran, Kubra; Karacan, Nurcan (SPRINGER BIRKHAUSER, 2011)A new series of disulfonamides were synthesized and assayed as antimicrobial agents against Staphylococcus aureus, Bacillus cereus, and Escherichia coli. The quantitative structure-activity relationship analysis (QSAR) was ... -
Structure, antibacterial activity and theoretical study of 2-hydroxy-1-naphthaldehyde-N-methylethanesulfonylhydrazone
Ozbek, Neslihan; Kavak, Guelten; Ozcan, Yusuf; Ide, Semra; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2009)2-Hydroxy-1-naphthaldehyde-N-methylethanesulfonylhydrazone was synthesized and its structure was investigated by X-ray diffraction. IR, NMR and mass spectroscopies. it crystallizes in the monoclinic system, space group ... -
Synthesis of benzimidazole derivatives containing amide bond and biological evaluation as acetylcholinesterase, carbonic anhydrase I and II inhibitors
Alım, Zuhal; Tunç, Turgay; Demirel, Nadir; Günel, Aslıhan; Karacan, Nurcan (Elsevier B.V., 2022)Acetylcholinesterase (AChE) and carbonic anhydrase I (CA-I) and II (CA-II) are two vital metabolic enzymes. AChE inhibitors are seen as target molecules in drug development studies for Alzheimer's treatment. CA inhibitors ... -
Synthesis, characterization and anti-microbial evaluation of Cu(II), Ni(II), Pt(II) and Pd(II) sulfonylhydrazone complexes; 2D-QSAR analysis of Ni(II) complexes of sulfonylhydrazone derivatives
Ozbek, Neslihan; Alyar, Saliha; Alyar, Hamit; Sahin, Ertan; Karacan, Nurcan (PERGAMON-ELSEVIER SCIENCE LTD, 2013)Copper(II), nickel(II), platinum(II) and palladium(II) complexes with 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) derived from propanesulfonic acid-1 -methylhydrazide (psmh) were synthesized, their ... -
Synthesis, characterization and antimicrobial activity of m-toluenesulfonamide, N,N '-1,2-ethanediylbis (mtsen) and [Cu(II)(phenanthroline)(2)]mtsen complex
Alyar, Hamit; Alyar, Saliha; Unal, Arslan; Ozbek, Neslihan; Sahin, Ertan; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2012)M-toluenesulfonamide, N,N'-1,2-ethanediylbis (a disulfonamide compound, mtsen) and [Cu(II)(phenanthroline)(2)]mtsen compounds were newly synthesized. The molecular structure of mtsen was investigated by using elemental ... -
Synthesis, characterization and antimicrobial activity of new aliphatic sulfonamide (vol 15, pg 5105, 2007)
Ozbek, Nelihan; Katircioglu, Hikmet; Karacan, Nurcan; Bayakal, Tuelay (PERGAMON-ELSEVIER SCIENCE LTD, 2007)… -
Synthesis, characterization and antimicrobial activity of new butanesulfonamides
Ozbek, Neslihan; Alyar, Saliha; Karacan, Nurcan (PROUS SCIENCE, SA, 2007)… -
Synthesis, characterization, and antibacterial activity of the ligands including thiophene/furan ring systems and their Cu(II), Zn(II) complexes
Gunduzalp, Ayla Balaban; Ozbek, Neslihan; Karacan, Nurcan (SPRINGER BIRKHAUSER, 2012)Carboxamide complexes having general formula as [ML]Cl-2 center dot nH(2)O (where M = Cu(II), Zn(II); n = 0, 1/2) were synthesized using heterocyclic carboxamide ligands: 1,4-bis[3-(2-thiophenecarboxamido)propyl]piperazine ... -
Synthesis, characterization, and antimicrobial activity of copper(II) complexes with N,N '-propanediyl-bis-benzenesulfonamide and N,N '-ethanediyl-bis-2-methylbenzenesulfonamide
Alyar, Saliha; Ozbek, Neslihan; Iskeleli, Nazan Ocak; Karacan, Nurcan (SPRINGER BIRKHAUSER, 2013)Copper(II) complexes of new aryldisulfonamides (L (1) = N,N'-bis[(2-methylphenyl)sulfonyl]ethylenediamine) and L (2) = N,N'-propanediyl-bis-benzenesulfonamide with 1,10-phenanthroline have been synthesized and characterized ... -
Synthesis, characterization, DFT studies of piperazine derivatives and its Ni(II), Cu(II) complexes as antimicrobial agents and glutathione reductase inhibitors
Ozbek, Neslihan; Mamas, Serhat; Erdogdu, Turkan; Alyar, Saliha; Kaya, Kerem; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2018)1,4-Piperazinediacetic acid and 1,4-diethyl ester (1) were prepared by treating 1,4-piperazine with ethylchloroacetate; and its structure was identified by single crystal X-ray diffraction analysis. Then, 1,4piperazinediacetic ... -
Synthesis, characterization, spectroscopic properties, theoretical calculation, and antimicrobial activity of new aryldisulfonamides
Alyar, Saliha; Zengin, Huseyin; Ozbek, Neslihan; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2011)New aryldisulfonamides were synthesized and characterized by FTIR, (1)H NMR, (13)C NMR, HETCOR, COSY, LC-MS and elemental analysis techniques. The compounds gave intense emissions, where lambda(max) = 405, 379 and 402 nm, ... -
Synthesis, crystal structure, antibacterial activities, and electrochemical studies of new N,N '-polymethylene bis-sulfonamides
Ozbek, Neslihan; Alyar, Saliha; Mamas, Serhat; Sahin, Ertan; Karacan, Nurcan (ELSEVIER SCIENCE BV, 2012)Four disulfonamide derivatives (C2H5 center dot SO2 center dot NH)(2)(CH2)(n) (n = 2, 3, 4, 5) were synthesized and characterized by FTIR, H-1 NMR, C-13 NMR, HETCOR, LCMS and elemental analysis.Ethanesulfonamide-N,N'-pen ...
