• Triad Pyrazole–Thiazole–Coumarin Heterocyclic Core Effectively İnhibit HSP and Drive Cancer Cells to Apoptosis 

  Gümüş, Mehmet; Koca, İrfan; Sert, Yusuf; Yenilmez Tunoğlu, Ezgi Nurdan; Tutar, Lütfi; Tutar, Yusuf (Taylor and Francis Ltd., 2023)

  Intensive studies on hepatocellular carcinoma (HCC), which is spreading rapidly around the world and has a high mortality rate, is due to the lack of adequate preventive or curative treatment methods. Treating patients ...

• Records of Aureobasidium harposporum, Sarcophoma miribelii, and Stigmina dothideoides from Turkey 

  Erdoğdu, Makbule; Ulukapı, Merve; Karayel, Ali İhsan; Suludere, Zekiye (Mycotaxon Ltd, 2020)

  During field studies on the microfungi in Mucur District of Kırşehir Province, Aureobasidium harposporum, and Stigmina dothideoides were revealed as new records for Turkey; and Sarcophoma miribelii, previously recorded ...

• Pyrazolyl-Benzoxazinone Derivatives as Dual Hsp Inhibitors in Human Breast Cancer 

  Koca, İrfan; Kamacı, Volkan; Özsoy, Ceylan; ...; Kani, İbrahim; Tutar, Lütfi; Tutar, Yusuf (John Wiley and Sons Inc, 2022)

  Heat Shock Proteins (Hsps) play major role on the onset of several cancers. Metabolic rates of cancer cells are higher compared to that of untransformed cells. This accelerated rate force functional substrate proteins to ...

• Article Present and Future Salmonid Cytogenetics 

  Gaffaroğlu, Muhammet; Majtánová, Zuzana; Symonová, Radka; ...; Unal, Sevgi; Lajbner, Zdeněk; Ráb, Petr (MDPI AG, 2020)

  Salmonids are extremely important economically and scientifically; therefore, dynamic developments in their research have occurred and will continue occurring in the future. At the same time, their complex phylogeny and ...

• Determination of Potential Drug Candidate Molecules of the Hypericum perforatum for COVID-19 Treatment 

  Yalçın, Serap; Yalçınkaya, Seda; Ercan, Fahriye (Springer Science and Business Media Deutschland GmbH, 2021)

  The novel human coronavirus was firstly emerged in December 2019 in Wuhan, China, and has spread rapidly around the world. There is no known specific effective treatment of COVID-19. The most commonly used agents against ...

• Karyology of an Endemic Oxynoemacheilus Simavicus (Balık & Bănărescu, 1978) (Teleostei: Nemacheilidae) 

  Karasu Ayata, Muradiye; Ünal Karakuş, Sevgi; Gaffaroğlu, Muhammet (Iranian Society of Ichthyology, 2021)

  The diploid chromosome number and chromosome morphologies of endemic Oxynoemacheilus simavicus (Balık & Bănărescu, 1978) were revealed out from Gediz River, Turkey. Metaphase chromosomes were obtained from head kidney ...

• In Silico Approach to Identify the Relationships between COVID-19 and Coronary Artery Disease/Rheumatoid Arthritis 

  Akçay, Sevinç; Pirim, Dilek (Instituto de Tecnologia do Parana, 2023)

  Global public has been threatened by the coronavirus disease 2019 (COVID-19) pandemic which led to nearly 15 million deaths around the world. People with complex and chronic diseases usually have more severe COVID-19 ...

• Taxonomic Notes on Smicronyx Schoenherr, 1843 (Coleoptera: Curculionidae) from Turkey 

  Erbey, Mahmut; Bolu, Halil (Georgia Entomological Society Inc., 2021)

  Four species of the genus Smicronyx Schoenherr (Coleoptera: Curculionidae) were examined in this study with Smicronyx albosquamosus Wollaston, S. coecus Reich, and S. syriacus Faust reported for the first time in Turkey. ...

• Histomorphology of the Male Reproductive System and Spermatogenesis of Phyllobius (Ectomogaster) fulvago Gyllenhal, 1834 (Coleoptera, Curculionidae): A Light and Scanning Electron Microscope Study 

  Erbey, Mahmut; Koçakoğlu, N. Özyurt; Candan, S. (Pleiades journals, 2021)

  Abstract: The morphology and histology of the male reproductive system of Phyllobius fulvago were described and discussed in relation to other Coleoptera species. The results show that Ph. fulvago has two-lobed flower-shaped ...

• Effect of PDYN rs2281285, rs2235749 and rs910080 gene polymorphisms on the intensity of depression symptoms and negative craving in heroin addicts 

  Kaya-Akyüzlü, Dilek; Özkan-Kotiloğlu, Selin; Yalçın-Şahiner, Şafak; Ayaz, Nagihan (Institut za Bioloska Istrazivanja, 2021)

  The present study was undertaken to explore whether prodynorphin (PDYN) polymorphisms have an effect on the intensity of depressive symptoms and negative craving in heroin addicts in a sample of 100 heroin addicts and 108 ...

• OPRD1 rs569356 polymorphism has an effect on plasma norbuprenorphine levels and dose/kg-normalized norbuprenorphine values in individuals with opioid use disorder 

  Kaya-Akyüzlü, Dilek; Özkan-Kotiloğlu, Selin; Danışman, Mustafa; Bal, Ceylan; Oğur, Begüm; İspir, Gamze Zengin (Elsevier B.V., 2023)

  This study aimed to determine the effects of nine OPRM1, OPRD1 and OPRK1 polymorphisms on plasma BUP and norbuprenorphine (norBUP) concentrations and various treatment responses in a sample of 122 patients receiving ...

• MicroRNAs and Heat Shock Proteins in Breast Cancer Biology 

  Yıldız, Mehmet Taha; Tutar, Lütfi; Giritlioğlu, Nazlı Irmak; Bayram, Banu; Tutar, Yusuf (Humana Press Inc., 2022)

  Breast cancer has five major immune types; luminal A, luminal B, HER2, Basal-like, and normal-like. Cells produce a family of protein called heat shock proteins (Hsps) in response to exposure to thermal and other proteotoxic ...

• Effect of bionanocomposites on human health 

  Yıldırım, Mehmethan; Yalçın, Serap (Elsevier, 2022)

  Nanotechnology is a major scientific area that has important potential to produce innovative material and this technology especially shows itself in biomedical research. Bionanocomposites occur with conjugates of biopolymers ...

• Karyomorphology of Two Cyprinid Barbels (Teleostei: Cyprinidae) from Gediz River, Turkey 

  Gaffaroğlu, Muhammet; Karasu-Ayata, Muradiye; Unal-Karakus, Sevgi (Allerton Press Inc., 2022)

  Abstract: Barbus pergamonensis Karaman, 1971 and Luciobarbus lydianus (Boulenger, 1896) were studied karyologically. Karyotypes and chromosomal banding techniques with C-banding and silver staining were determined. Diploid ...

• Isolation and identification of bacillus pumilus yhh-2, a potential pathogen to the alfalfa weevil (Hypera postica gyllenhal) 

  Öğütçü, Hatice; Erbey, Yasemin; Güllüce, Medine; Alaylar, Burak; Karadayi, Mehmet; Sezen, Selma; Erbey, Mahmut (Turkiye Klinikleri, 2020)

  Alfalfa weevil (Hypera postica Gyllenhal, 1813) samples were collected from different locations in Kırşehir, Turkey, during May–August in 2014. They were immediately transferred to the research laboratory and dissected ...

• Are BPA-free plastics safe for aquatic life?-Fluorene-9-bisphenol induced thyroid-disrupting effects and histopathological alterations in adult zebrafish (Danio rerio) 

  Özkan-Kotiloğlu, Selin; Arslan, Pınar; Akça, Gülçin; Günal, Aysel Çağlan (Elsevier Scıence Inc, 2022)

  Fluorene-9-bisphenol (BPFL) is used as an alternative compound for bisphenol A, an endocrine disruptor compound which is present in various materials including plastic bottles and packaging. Although it is used extensively ...

• Pentastira eminei sp. nov. (Hemiptera, Fulgoromorpha, Cixiidae) from Turkiye, and notes on other Pentastira spp. in Turkiye and the Middle East 

  Demirel, Ersin; Erbey, Mahmut (Magnolia Press, 2022)

  Pentastira eminei sp. nov. (Hemiptera, Auchenorrhyncha, Fulgoromorpha, Cixiidae) from Central Anatolia, Turkiye is described and the status of the genus in Turkiye reevaluated. Pentastira superans Logvinenko, 1976 in ...

• Sublingual buprenorphine/naloxone treatment is not affected by OPRM1 A118G and BDNF Va66Met polymorphisms, but alters the plasma beta-endorphin and BDNF levels in individuals with opioid use disorder 

  Kaya-Akyüzlü, Dilek; Özkan-Kotiloğlu, Selin; Bal, Ceylan; Avcıoğlu, Gamze; Şahiner, Şafak Yalçın; Şahiner, İsmail Volkan (Elsevier B.V., 2022)

  The study aimed to examine the genetic contribution to buprenorphine (BUP) treatment in individuals with opioid use disorder (OUD), with a specific focus on BDNF and OPRM1 genes. A total of 113 controls and 111 OUD patients ...

• Are BPA-free plastics safe for aquatic life? - Fluorene-9-bisphenol induced thyroid-disrupting effects and histopathological alterations in adult zebrafish (Danio rerio) 

  Özkan-Kotiloğlu, Selin; Arslan, Pınar; Akça, Gülçin; Günal, Aysel Çağlan (Elsevier Inc., 2022)

  Fluorene-9-bisphenol (BPFL) is used as an alternative compound for bisphenol A, an endocrine disruptor compound which is present in various materials including plastic bottles and packaging. Although it is used extensively ...

• Ribosomal and Protein Gene Phylogeny Reveals Novel Saprobic Fungal Species FromJuglans regiaandUrtica dioica 

  Pem, Dhandevi; Jeewon, Rajesh; Selcuk, Faruk; Ulukapi, Merve; Bhat, Jayarama; Doilom, Mingkwan; Lumyong, Saisamorn; Hyde, Kevin D. (Frontıers Medıa Sa, 2020)

  During an ongoing investigation of Ascomycetes from plant substrates, three saprobic species were found from plant substrates. Two new species,Leptosphaeria regiaeandNeomicrosphaeropsis juglandiswere isolated from dead ...

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