Başlık için Moleküler Biyoloji ve Genetik listeleme
Toplam kayıt 39, listelenen: 1-20
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Alginate-based bionanocomposites for cancer therapy
(Elsevier, 2022)Alginate is a natural polymer widely produced by extraction from brown seaweeds. In recent years, the alginate-based systems have been designed and characterized as gels, matrices, membranes, beads, pellets, fibers, ... -
Antiproliferative activity and interaction with proteins of N-cyclohexylacrylamide
(Elsevier B.V., 2022)N-cyclohexylacrylamıde (NCA), the synthesized compound, was evaluated for their cytotoxic activities against HeLa cancer cell line. Also, the current study has been analyzed by the use of molecular docking as protein-ligand ... -
Are BPA-free plastics safe for aquatic life? - Fluorene-9-bisphenol induced thyroid-disrupting effects and histopathological alterations in adult zebrafish (Danio rerio)
(Elsevier Inc., 2022)Fluorene-9-bisphenol (BPFL) is used as an alternative compound for bisphenol A, an endocrine disruptor compound which is present in various materials including plastic bottles and packaging. Although it is used extensively ... -
Are BPA-free plastics safe for aquatic life?-Fluorene-9-bisphenol induced thyroid-disrupting effects and histopathological alterations in adult zebrafish (Danio rerio)
(Elsevier Scıence Inc, 2022)Fluorene-9-bisphenol (BPFL) is used as an alternative compound for bisphenol A, an endocrine disruptor compound which is present in various materials including plastic bottles and packaging. Although it is used extensively ... -
Association of PDYN 68-bp VNTR polymorphism with sublingual buprenorphine/naloxone treatment and with opioid or alcohol use disorder: Effect on craving, depression, anxiety and age onset of first use
(Elsevier, 2022)In this case-control study (423 Turkish subjects), the functional pro-dynorphin (PDYN) 68-bp VNTR polymorphism was genotyped in opioid users receiving sublingual buprenorphine/naloxone treatment (SBNT; n = 129, 119 males ... -
Bioinformatics analysis of molecular pathways and key candidate biomarkers associated with human bone marrow hematopoietic stem cells (HSCs) micro-array gene expression data
(Elsevier B.V., 2022)An identification of the molecular properties of glioma stem cells (GSCs) has led studies in clinical use, stem cell identification, and highly-effective usage. The GSE32719 contains a total expression of 54,676 genes of ... -
BRAF mutation in colorectal carcinomas with signet ring cell component
(CHINESE ANTI-CANCER ASSOC, 2017)Objective: Signet ring cell carcinoma is a rare subtype of colorectal carcinoma (CRC) with an associated BRAFV600E mutation. We investigated frequencies of BRAF mutation in 28 CRCs containing variable signet ring cell ... -
Characterization of gemcitabine loaded polyhydroxybutyrate coated magnetic nanoparticles for targeted drug delivery
(Bentham Science Publishers, 2020)Background: Targeted drug delivery is one of the recent hot topics in cancer therapy. Because of having a targeting potential under the magnetic field and a suitable surface for the attachment of different therapeutic ... -
The Cisplatin, 5-fluorouracil, Irinotecan, and Gemcitabine Treatment in Resistant 2D and 3D Model Triple Negative Breast Cancer Cell Line: ABCG2 Expression Data
(Bentham Scıence Publ Ltd, 2022)Background: Chemotherapeutics have been commonly used in cancer treatment. Objective: In this study, the effects of Cisplatin, 5-fluorouracil, Irinotecan, and Gemcitabine have been evaluated on two-dimensional (2D) (sensitive ... -
Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis
(BENTHAM SCIENCE PUBL LTD, 2016)Background: Despite development of novel cancer drugs, invasive ductal breast carcinoma and its metastasis are still highly morbid. Therefore, new therapeutic approaches are being developed and Hsp90 is an important target ... -
Determination of the effect of L. plantarum AB6-25, L. plantarum MK55 and S. boulardii T8-3C microorganisms on colon, cervix, and breast cancer cell lines: Molecular docking, and molecular dynamics study
(Elsevier B.V., 2022)Cancer constitutes an important part of the diseases that are caused all over the world. Due to the side effects of commonly used treatment options such as chemotherapy and radiotherapy, there has been a tendency to seek ... -
DETERMINATION OF THE RELATIONSHIP BETWEEN DOXORUBICIN RESISTANCE AND WNT SIGNALING PATHWAY IN HELA AND K562 CELL LINES
(EXCLI JOURNAL MANAGING OFFICE, 2018)Activation of the Wnt signaling in some types of cancer and its relation with chemotherapy resistance is a very interesting issue that has been emphasized in recent years. Although, it is known that increase in the activity ... -
Dextran-coated iron oxide nanoparticle for delivery of miR-29a to breast cancer cell line
(TAYLOR & FRANCIS LTD, 2019)In the last years, miRNAs have been associated with molecular pathways of cancer and other diseases. The change of expression level of miRNA has an inhibitory role in tumorigenesis. Nevertheless, the poor bioavailability ... -
Effect of bionanocomposites on human health
(Elsevier, 2022)Nanotechnology is a major scientific area that has important potential to produce innovative material and this technology especially shows itself in biomedical research. Bionanocomposites occur with conjugates of biopolymers ... -
The Effect of Gaussian Noise on Maximum Likelihood Fitting of Gompertz and Weibull Mortality Models with Yeast Lifespan Data
(TAYLOR & FRANCIS INC, 2019)Background/study context: Empirical lifespan data sets are often studied with the best-fitted mathematical model for aging. Here, we studied how experimental noises can influence the determination of the best-fitted aging ... -
Effect of PDYN rs2281285, rs2235749 and rs910080 gene polymorphisms on the intensity of depression symptoms and negative craving in heroin addicts
(Institut za Bioloska Istrazivanja, 2021)The present study was undertaken to explore whether prodynorphin (PDYN) polymorphisms have an effect on the intensity of depressive symptoms and negative craving in heroin addicts in a sample of 100 heroin addicts and 108 ... -
Effects of UGT2B7 rs7662029 and rs7439366 polymorphisms on sublingual buprenorphine metabolism in heroin addicts: An improved PCR-RFLP assay for the detection of rs7662029 polymorphism
(Elsevier, 2022)This study aimed to determine the effects of UGT2B7 rs7662029 and rs7439366 polymorphisms on plasma buprenorphine (BUP) concentration and different treatment responses in a sample of 109 patients with opioid use disorder ... -
Folic acid functionalized PEG coated magnetic nanoparticles for targeting anti-cancer drug delivery: Preparation, characterization and cytotoxicity on Doxorubicin, Zoledronic acid and Paclitaxel resistant MCF-7 breast cancer cell lines
(TAYLOR & FRANCIS INC, 2018)In this study, MNPs were synthesized, coated with biocompatible polyethylene glycol (PEG) and conjugated with folic acid. Crystal and chemical structures, shape, size and magnetic properties of synthesized nanoparticles ... -
Histomorphology of the Male Reproductive System and Spermatogenesis of Phyllobius (Ectomogaster) fulvago Gyllenhal, 1834 (Coleoptera, Curculionidae): A Light and Scanning Electron Microscope Study
(Pleiades journals, 2021)Abstract: The morphology and histology of the male reproductive system of Phyllobius fulvago were described and discussed in relation to other Coleoptera species. The results show that Ph. fulvago has two-lobed flower-shaped ... -
In Silico Approach to Identify the Relationships between COVID-19 and Coronary Artery Disease/Rheumatoid Arthritis
(Instituto de Tecnologia do Parana, 2023)Global public has been threatened by the coronavirus disease 2019 (COVID-19) pandemic which led to nearly 15 million deaths around the world. People with complex and chronic diseases usually have more severe COVID-19 ...
