Yayın tarihi için Tıbbi Biyoloji AD listeleme
Toplam kayıt 28, listelenen: 1-20
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Does long-term talc exposure have a carcinogenic effect the female genital system of rats? An experimental pilot study
(SPRINGER HEIDELBERG, 2009)Objective In several studies, the prolonged exposure to talc has been associated with development of ovarian cancer. However, some studies have advocated contrary views. The present study aims to investigate histopathological ... -
Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome
(ELSEVIER, 2015)Objective: Fibromyalgia syndrome (FM) is a common disease characterized by generalized body pain, sensitivity in certain physical areas (sensitive points), lowered pain threshold, sleep disorder, and fatigue. The study ... -
Genotoxic Effects of Prenatal Exposure to Levetiracetam During Pregnancy on Rat Offsprings
(INT INST ANTICANCER RESEARCH, 2015)Levetiracetam is a new-generation antiepileptic drug initially approved as an adjunctive treatment for patients with refractory partial seizures and is now also used as a monotherapy. The aim of this study was to evaluate ... -
Effects of subtelomeric copy number variations in miscarriages
(TAYLOR & FRANCIS LTD, 2015)Purpose: This study was performed on miscarriage samples for chromosome analysis to detect copy number variations (CNVs) related to subtelomeric regions, and with these results we aimed to adapt multiplex ligation-dependent ... -
The Effect of IL-4 Gene Polymorphism in Carpal Tunnel Syndrome
(DERMAN MEDICAL PUBL, 2016)Aim: Carpal tunnel syndrome (CTS) is a neurological disorder characterized by paresthesia and pain in the hands due to lesions and /or dysfunction of the median nerve at the wrist. The exact pathogenesis of CTS is not ... -
Evaluation of MIF-173 G/C Polymorphism in Turkish Patients with Ankylosing Spondylitis
(GALENOS YAYINCILIK, 2016)Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the spine and sacroiliac joints. Macrophage migration inhibitory (MIF) factor is a regulatory cytokine that inhibits random immune ... -
Relationship between major depressive disorder and ACE gene I/D polymorphism in a Turkish population
(UNIV SAO PAULO, INST PSIQUIATRIA, 2016)Background: Major depressive disorder (MDD) is a complex disease and a significant health problem that is prevalent across the world. Angiotensin-converting enzyme (ACE) has an important role in renin-angiotensin system ... -
In Silico Analysis of FMR1 Gene Missense SNPs
(HUMANA PRESS INC, 2016)The FMR1 gene, a member of the fragile X-related gene family, is responsible for fragile X syndrome (FXS). Missense single-nucleotide polymorphisms (SNPs) are responsible for many complex diseases. The effect of FMR1 gene ... -
Interleukin-1Ra rs2234663 and Interleukin-4 rs79071878 Polymorphisms in Familial Mediterranean Fever
(ELSEVIER SCIENCE BV, 2016)Objective: Familial Mediterranean Fever (FMF) is an autosomal recessively inherited auto inflammatory disorder. MEFV gene, causing FMF, encodes pyrin that is associated with the interleukin-1 (IL-1) related inflammation ... -
Mutational Spectrum of the MEFV Gene in AA Amyloidosis Associated With Familial Mediterranean Fever
(IRANIAN SOC NEPHROLGY, 2016)Introduction. Familial Mediterranean fever (FMF) is a recessively inherited disease which is characterized by recurrent episodic fever, abdominal pain, and polyserositis. It is caused by mutations in the MEFV gene, encoding ... -
Investigation of CD40 gene rs4810485 and rs1883832 mutations in patients with recurrent aphthous stomatitis
(PERGAMON-ELSEVIER SCIENCE LTD, 2017)Objectives: Recurrent aphthous stomatitis (RAS) is a common painful disorder affecting oral health, mucosa and overall quality of life. The etiopathogenesis of RAS remains unclear. RAS shows a large genetic diversity among ... -
Evaluation of apoptotic cell death on liver and kidney tissues following administration of levetiracetam during prenatal period
(TAYLOR & FRANCIS LTD, 2017)Objective: Levetiracetam is a new generation antiepileptic drug used in treatment of patients with epilepsy and has adverse effects on different tissues. We aimed to evaluate the apoptotic effects of levetiracetam exposure ... -
Importance of NPC1 Gene 644 A -> G Mutation in Coronary Artery Disease
(KAMLA-RAJ ENTERPRISES, 2017)Coronary artery disease (CAD) is the most prominent cause of mortality worldwide. The basis of CAD pathogenesis is the occlusion of coroner vessels progressively due to atherosclerotic plaques. NPCI gene plays a critical ... -
Impact of glucocorticoid receptor gene Bcl-1 variant on temporomandibular disorders
(Scientific Publishers of India, 2017)Objectives: Temporomandibular Disorders (TMD) constitute a heterogeneous group of disorders characterized by alterations in mandibular movement. The aim of this study was to investigate the association between the Bcl1 ... -
The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population
(WILEY, 2018)BackgroundTemporomandibular joint disorders (TMD) are a group of disorders involving temporomandibular joint and related structures. Interleukine-1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule ... -
Macrophage Migration Inhibitory Factor-173GC Variant Might Increase the Risk of Behcet's Disease
(KARGER, 2018)Objective: The aim of the present study was to investigate any possible association between the macrophage migration inhibitory factor (MIF) -173GC variant and Behcet's disease (BD) in a group of Turkish patients. Subjects ... -
The investigation of association between IL-1Ra and ACE I/D polymorphisms in carpal tunnel syndrome
(WILEY, 2018)BackgroundCarpal tunnel syndrome (CTS) is a common neurologic impairment caused by injury on the median nerve in the wrist, characterized by pain and loss of sensory. CTS usually occurs through three factors, such as a ... -
Angiotensin Converting Enzyme Gene Insertion/Deletion Variant and Familial Mediterranean Fever-related Amyloidosis
(IRANIAN SOC NEPHROLGY, 2018)Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ... -
Angiotensin converting enzyme gene insertion/deletion variant and familial Mediterranean fever-related amyloidosis
(Iranian Society of Nephrology, 2018)Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ... -
Effect of a functional variant of tumor necrosis factor-beta gene in temporomandibular disorders: A pilot study
(WILEY, 2019)Background Temporomandibular disorders (TMD) are a group of conditions that cause chronic orofacial pain. The tumor necrosis factor beta (TNF-beta) is a proinflammatory cytokine that is involved in the various aspects of ...
