Browsing Yayın Koleksiyonu by Title
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Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome
(ELSEVIER, 2015)Objective: Fibromyalgia syndrome (FM) is a common disease characterized by generalized body pain, sensitivity in certain physical areas (sensitive points), lowered pain threshold, sleep disorder, and fatigue. The study ... -
Angiotensin Converting Enzyme Gene Insertion/Deletion Variant and Familial Mediterranean Fever-related Amyloidosis
(IRANIAN SOC NEPHROLGY, 2018)Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ... -
Angiotensin converting enzyme gene insertion/deletion variant and familial Mediterranean fever-related amyloidosis
(Iranian Society of Nephrology, 2018)Introduction. The most important complication of familial Mediterranean fever (FMF) is secondary amyloidosis, which can lead to kidney failure. Genetic variability in the genes of various components of the renin-angiotensin ... -
Association of XRCC1 and XPD functional gene variants with nicotine dependence and/or schizophrenia: a case-control study and in silico analysis
(TAYLOR & FRANCIS LTD, 2019)OBJECTIVE: The role of DNA repair mechanisms has received attention recently in schizophrenia (Sch). Sch patients show an increased prevalence of nicotine dependence (ND). This study aimed to find out whether functional ... -
Does long-term talc exposure have a carcinogenic effect the female genital system of rats? An experimental pilot study
(SPRINGER HEIDELBERG, 2009)Objective In several studies, the prolonged exposure to talc has been associated with development of ovarian cancer. However, some studies have advocated contrary views. The present study aims to investigate histopathological ... -
Dual delivery of platelet-derived growth factor and bone morphogenetic factor-6 on titanium surface to enhance the early period of implant osseointegration
(Blackwell Munksgaard, 2020)Objective: To test the surface properties and in vitro effects of a new sequential release system on MC3T3-E1 cells for improved osseointegration. Background: BMP6-loaded anodized titanium coated with PDGF containing silk ... -
Effect of a functional variant of tumor necrosis factor-beta gene in temporomandibular disorders: A pilot study
(WILEY, 2019)Background Temporomandibular disorders (TMD) are a group of conditions that cause chronic orofacial pain. The tumor necrosis factor beta (TNF-beta) is a proinflammatory cytokine that is involved in the various aspects of ... -
The Effect of IL-4 Gene Polymorphism in Carpal Tunnel Syndrome
(DERMAN MEDICAL PUBL, 2016)Aim: Carpal tunnel syndrome (CTS) is a neurological disorder characterized by paresthesia and pain in the hands due to lesions and /or dysfunction of the median nerve at the wrist. The exact pathogenesis of CTS is not ... -
Effects of subtelomeric copy number variations in miscarriages
(TAYLOR & FRANCIS LTD, 2015)Purpose: This study was performed on miscarriage samples for chromosome analysis to detect copy number variations (CNVs) related to subtelomeric regions, and with these results we aimed to adapt multiplex ligation-dependent ... -
Evaluation of apoptotic cell death on liver and kidney tissues following administration of levetiracetam during prenatal period
(TAYLOR & FRANCIS LTD, 2017)Objective: Levetiracetam is a new generation antiepileptic drug used in treatment of patients with epilepsy and has adverse effects on different tissues. We aimed to evaluate the apoptotic effects of levetiracetam exposure ... -
Evaluation of MIF-173 G/C Polymorphism in Turkish Patients with Ankylosing Spondylitis
(GALENOS YAYINCILIK, 2016)Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the spine and sacroiliac joints. Macrophage migration inhibitory (MIF) factor is a regulatory cytokine that inhibits random immune ... -
Genotoxic Effects of Prenatal Exposure to Levetiracetam During Pregnancy on Rat Offsprings
(INT INST ANTICANCER RESEARCH, 2015)Levetiracetam is a new-generation antiepileptic drug initially approved as an adjunctive treatment for patients with refractory partial seizures and is now also used as a monotherapy. The aim of this study was to evaluate ... -
GO containing PHBHX bone scaffold: GO concentration and in vitro osteointegration
(Springer Science and Business Media Deutschland GmbH, 2022)Trauma, congenital abnormalities or cancer-induced bone defects can be treated with tissue engineering products. Graphene oxide-containing polymeric scaffolds are used as an artificial extracellular matrix, acting as an ... -
The IL-1Ra gene variable number tandem repeat variant is associated with susceptibility to temporomandibular disorders in Turkish population
(WILEY, 2018)BackgroundTemporomandibular joint disorders (TMD) are a group of disorders involving temporomandibular joint and related structures. Interleukine-1 receptor antagonist (IL-1Ra) is an important anti-inflammatory molecule ... -
Impact of glucocorticoid receptor gene Bcl-1 variant on temporomandibular disorders
(Scientific Publishers of India, 2017)Objectives: Temporomandibular Disorders (TMD) constitute a heterogeneous group of disorders characterized by alterations in mandibular movement. The aim of this study was to investigate the association between the Bcl1 ... -
Importance of NPC1 Gene 644 A -> G Mutation in Coronary Artery Disease
(KAMLA-RAJ ENTERPRISES, 2017)Coronary artery disease (CAD) is the most prominent cause of mortality worldwide. The basis of CAD pathogenesis is the occlusion of coroner vessels progressively due to atherosclerotic plaques. NPCI gene plays a critical ... -
In Silico Analysis of FMR1 Gene Missense SNPs
(HUMANA PRESS INC, 2016)The FMR1 gene, a member of the fragile X-related gene family, is responsible for fragile X syndrome (FXS). Missense single-nucleotide polymorphisms (SNPs) are responsible for many complex diseases. The effect of FMR1 gene ... -
Increased serum myonectin and irisin levels with myonectin and FNDC5 expressions in polycystic ovary syndrome: a case control study
(Taylor and Francis Ltd., 2022)The aim of this study is to assess the FNDC5 and myonectin expressions and serum levels of myonectin and irisin in women with PCOS. 90 participants were included in this case-control study. 45 of these participants were ... -
Interleukin-1Ra rs2234663 and Interleukin-4 rs79071878 Polymorphisms in Familial Mediterranean Fever
(ELSEVIER SCIENCE BV, 2016)Objective: Familial Mediterranean Fever (FMF) is an autosomal recessively inherited auto inflammatory disorder. MEFV gene, causing FMF, encodes pyrin that is associated with the interleukin-1 (IL-1) related inflammation ... -
The investigation of association between IL-1Ra and ACE I/D polymorphisms in carpal tunnel syndrome
(WILEY, 2018)BackgroundCarpal tunnel syndrome (CTS) is a common neurologic impairment caused by injury on the median nerve in the wrist, characterized by pain and loss of sensory. CTS usually occurs through three factors, such as a ...
