Kırşehir Ahi Evran Üniversitesi Kurumsal Akademik Arşivi
DSpace@Kırşehir, Kırşehir Ahi Evran Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisimi artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
An end-to-end deep learning pipeline for urban noise monitoring with spatiotemporal analysis
(Nature Research, 2026) Yalçınkaya, Mehmet Ali
Urban noise pollution is a critical public health problem affecting millions of people around the world. Current acoustic monitoring systems largely focus on optimizing classification accuracy but fail to meet operational requirements such as calibrated probability outputs, deployment formats, and spatiotemporal integration. This study presents a comprehensive urban noise monitoring pipeline extending from raw sensor data to city-scale policy support. The proposed framework uses a CNN14-based ensemble architecture on the SONYC-UST dataset collected from 56 acoustic sensors deployed across New York City. The system performs simultaneous multi-source detection across 35 hierarchical acoustic presence labels and provides reliable probability calibration validated by a Brier score of 0.1269. In terms of technical infrastructure, the pipeline offers export in TorchScript format that can run on edge devices without Python dependency, processing capacity of more than 2,000 audio segments per second on an NVIDIA GeForce RTX 3060 and training time of less than six hours per fold. Integrated 250-meter spatial grid mapping and hourly-daily temporal aggregation modules enable direct integration of predictions into urban planning workflows. Independent external corroboration was performed using NYC 311 complaint records across 3,460 matched grid-day observations. Permutation testing revealed a statistically significant relationship between predicted noise scores and community-reported disturbance. This study demonstrates that model accuracy alone is not sufficient for deployable urban noise monitoring systems, and that a holistic approach encompassing calibration, deployment, and spatial integration is required.
The investigation of the basic psychological needs of athletes in the Turkish National Amputee Football Team: a qualitative study
(Frontiers Media SA, 2026) Kara, Ersan
Introduction – The aim of this study is to examine the experiences of athletes in the Turkish Amputee National Football Team regarding the dimensions of autonomy, competence, and relatedness, which are their basic psychological needs. Method – The research was designed within the framework of a qualitative research approach, and the participant group consists of nine athletes who are actively involved in the Turkish Amputee National Football Team. The participants consist of individuals with different levels of amputation. The data were collected through semi-structured interviews and observations conducted during training and competition processes. The interviews were conducted face-to-face, audio-recorded, and later transcribed into written texts. The obtained data were analyzed using the thematic analysis method. As a result of the analysis, five themes emerged: (1) autonomy and freedom of decision-making, (2) perception of competence and sense of achievement, (3) social bonds and belonging, (4) coping with disability and psychological resilience, and (5) performance pressure and internal-external tension. Results – The findings show that athletes’ motivation and self-confidence increase when their autonomy is supported; however, external pressures can limit this process. It was determined that the perception of competence is strengthened through performance opportunities and experiences of success, while social bonds are shaped through belonging, trust, and feeling valued. However, it was also observed that belonging is not always inclusive and is constructed through selective relationships. In addition, the findings reveal that psychological resilience is not only an individual trait but is shaped by social relationships and the sporting context. It was determined that athletes continuously try to maintain a balance between performance expectations and their intrinsic motivation, and that this situation sometimes creates tension. Discussion – The findings further demonstrate that amputee football simultaneously functions as a context of empowerment and psychological pressure, where athletes negotiate autonomy, competence, and belonging under conditions shaped by performance expectations and social evaluation. As a result, the study reveals that amputee football is both an empowering and limiting field of experience for athletes, and that sports environments should be restructured in a way that supports psychological needs.
Vaccine literacy and attitudes toward ımmunization among adults in primary care
(Associacao Medica Brasileira, 2026) Doğan, Birgül Deniz; Doğan, Murat
OBJECTIVE: Vaccine hesitancy continues to be a significant global public health issue, and our understanding of how vaccine literacy influences immunization attitudes is incomplete. The aim of this study was to evaluate vaccine literacy and attitudes toward immunization among adults in Central Anatolia, Turkey, and to examine the association between vaccine literacy dimensions and immunization attitudes. METHODS: A cross-sectional study was conducted between February and May 2025 among 928 adults attending Family Health Centers in Kırşehir. Data were collected through face-to-face interviews using a structured sociodemographic questionnaire, the Health Literacy about Vaccination in Adults Scale, and the Attitudes Toward Immunization Scale. Nonparametric tests, Spearman correlation analyses, and multiple linear regression were applied. RESULTS: Participants showed moderate levels across all vaccine literacy domains and moderately positive immunization attitudes. Correlations between Health Literacy about Vaccination in Adults Scale subscales and Attitudes Toward Immunization Scale scores were generally weak. Communicative vaccine literacy showed a weak but important negative relationship with the overall Attitudes Toward Immunization Scale score (r=-0.077, p=0.018) and the belief/opinion part (r=-0.121). In regression analysis, none of the vaccine literacy subscales significantly predicted immunization attitudes, and the model explained only 0.4% of the variance (Adjusted R2=0.004, p=0.090). CONCLUSION: Vaccine literacy alone has limited explanatory value for immunization attitudes. These findings indicate that attitudes are shaped by factors beyond cognitive literacy and suggest that interventions should extend beyond information provision.
Decidual senescence in recurrent pregnancy loss: forkhead box M1-targeted progesterone treatment
(Elsevier Ltd, 2026) Kendirci-Katirci, Remziye; Katirci, Ertan; Sanhal, Cem Y.; Kirtiş, Emine; Satı, Leyla; Çelik-Özenci, Çiler
Research question: What is the role of FOXM1 in the pathogenesis of recurrent pregnancy loss (RPL) characterized by increased decidual senescence, and how do two progesterone analogues (medroxyprogesterone acetate [MPA] and dydrogesterone [DYD]) modulate FOXM1 expression and associated senescence markers in an in-vitro decidualization model? Design: Primary decidual cells were isolated from decidual tissue samples collected from women with clinically healthy pregnancies that were terminated voluntarily (control pregnancy group, n = 10) and women with RPL (RPL group, n = 10). Cells were treated with MPA and DYD, and PRL and IGFBP-1 concentrations were analysed by ELISA. FOXO1, FOXM1, phospho-FOXM1 (p-FOXM1), DIO2 and β-GAL expression was examined by immunofluorescence. Co-culture experiments with AC-1M88 trophoblast-like cells assessed spheroid expansion and migration. Results: MPA and DYD treatments significantly ameliorated PRL (P = 0.006 and P = 0.015, respectively) and IGFBP-1 (both P < 0.001) concentrations, and FOXO1, FOXM1 and p-FOXM1 expression (all P < 0.001), in the RPL group. DYD treatment was more effective than MPA treatment in restoring FOXM1 and p-FOXM1 expression (both P < 0.001). MPA and DYD did not affect spheroid expansion in the RPL group but increased cell migration (p=0.009 and p<0.001, respectively); however, neither treatment significantly reduced DIO2 or β-GAL expression. Conclusions: Decidual cells from women with RPL exhibited reduced FOXM1 expression and increased senescence-associated markers. MPA and DYD restored FOXM1 expression and improved decidual function, but did not reverse senescence marker expression. These findings suggest that combining senomorphic agents with progesterone analogues may represent a promising avenue for future mechanistic and translational research.
Shilajit as a Natural Product from Sedimentary Rocks: Biological Origin and Antioxidant Properties
(Springer, 2026) Uluğ, Asiye; Yıldız Dalgınlı, Kezban; Özdemir Değirmenci, Funda; Öztürkler Dündar, Melek; Atakişi, Onur
Shilajit, a natural product with a documented history of use in traditional medicine for millennia, poses considerable challenges in elucidating its biological origin and pharmacological properties. In this study, a multidisciplinary approach integrating DNA metabarcoding and biochemical profiling was employed to investigate processed shilajit samples from the Pamir-Alai Mountains. Environmental DNA analysis identified 50 plant taxa across taxonomic levels ranging from order to species, indicating substantial botanical contributions to shilajit’s composition. Among the identified taxa, Apiaceae and Asteraceae were the most represented families, while Vincetoxicum rossicum, Populus alba, and Quercus suber were the dominant species detected through metabarcoding analysis. Complementary biochemical analyses demonstrated notable antioxidant capacity and the presence of diverse bioactive compounds. Furthermore, oxidative stress-related biomarkers (NO, MDA, and GSH) were evaluated in the brain tissue of healthy rats following shilajit administration. No statistically significant differences were observed between the control and shilajit treated groups, suggesting that shilajit maintains physiological oxidative balance in healthy brain tissue. These findings provide important baseline biochemical data and support future investigations of shilajit's biological effects in validated oxidative stress and neurological disease models.
