Identification and antifungal susceptibility of candida isolates from various clinical specimens in doctor Behçet uz hospital

Abstract

The purpose of this study was to identify and determine antifungal susceptibility patterns of 101 yeast strains isolated from varios clinical specimens. Identification of the isolates were determined by API 20 C AUX kit (Biomérieux, France) and antifungal susceptibilities of these species to flucytosine, amphotericin B, fluconazole, itraconazole and voriconazole were determined by API ATB Fungus kit (Biomérieux, France). Of the 101 strains, 48 were isolated from urine, 46 from blood, 5 from catheter and 2 from wound. C.albicans (54.46%) was the most frequently isolated species, followed by C.parapsilosis (33.66%), C.famata (6.93%), C.tropicalis (2.97%) and C.pelliculosa (1.98%). High rates of resistance against itraconazole, fluconazole and voricanozole were detected in C.albicans. Different rates of resistance against especially itraconazole were detected in other Candida strains. Species definition and determination of antifungal susceptibility patterns are advised for the proper treatment of Candida infections.