Başlık için Yayın Koleksiyonu listeleme
Toplam kayıt 45, listelenen: 1-20
-
Alginate-based bionanocomposites for cancer therapy
(Elsevier, 2022)Alginate is a natural polymer widely produced by extraction from brown seaweeds. In recent years, the alginate-based systems have been designed and characterized as gels, matrices, membranes, beads, pellets, fibers, ... -
Antiproliferative activity and interaction with proteins of N-cyclohexylacrylamide
(Elsevier B.V., 2022)N-cyclohexylacrylamıde (NCA), the synthesized compound, was evaluated for their cytotoxic activities against HeLa cancer cell line. Also, the current study has been analyzed by the use of molecular docking as protein-ligand ... -
Are BPA-free plastics safe for aquatic life? - Fluorene-9-bisphenol induced thyroid-disrupting effects and histopathological alterations in adult zebrafish (Danio rerio)
(Elsevier Inc., 2022)Fluorene-9-bisphenol (BPFL) is used as an alternative compound for bisphenol A, an endocrine disruptor compound which is present in various materials including plastic bottles and packaging. Although it is used extensively ... -
Are BPA-free plastics safe for aquatic life?-Fluorene-9-bisphenol induced thyroid-disrupting effects and histopathological alterations in adult zebrafish (Danio rerio)
(Elsevier Scıence Inc, 2022)Fluorene-9-bisphenol (BPFL) is used as an alternative compound for bisphenol A, an endocrine disruptor compound which is present in various materials including plastic bottles and packaging. Although it is used extensively ... -
Article Present and Future Salmonid Cytogenetics
(MDPI AG, 2020)Salmonids are extremely important economically and scientifically; therefore, dynamic developments in their research have occurred and will continue occurring in the future. At the same time, their complex phylogeny and ... -
Association of OPRK1 Rs963549 and Rs997917 Polymorphisms With Opioid use Disorder and Related Phenotypes
(Newlands Press Ltd, 2023)Aim: To evaluate the association between OPRK1 rs963549 and rs997917 and opioid use disorder (OUD) and related phenotypes. Methods: A sample of 208 individuals with (n = 100) and without (n = 108) OUD were enrolled. OPRK1 ... -
Association of PDYN 68-bp VNTR polymorphism with sublingual buprenorphine/naloxone treatment and with opioid or alcohol use disorder: Effect on craving, depression, anxiety and age onset of first use
(Elsevier, 2022)In this case-control study (423 Turkish subjects), the functional pro-dynorphin (PDYN) 68-bp VNTR polymorphism was genotyped in opioid users receiving sublingual buprenorphine/naloxone treatment (SBNT; n = 129, 119 males ... -
Bioinformatics analysis of molecular pathways and key candidate biomarkers associated with human bone marrow hematopoietic stem cells (HSCs) micro-array gene expression data
(Elsevier B.V., 2022)An identification of the molecular properties of glioma stem cells (GSCs) has led studies in clinical use, stem cell identification, and highly-effective usage. The GSE32719 contains a total expression of 54,676 genes of ... -
BRAF mutation in colorectal carcinomas with signet ring cell component
(CHINESE ANTI-CANCER ASSOC, 2017)Objective: Signet ring cell carcinoma is a rare subtype of colorectal carcinoma (CRC) with an associated BRAFV600E mutation. We investigated frequencies of BRAF mutation in 28 CRCs containing variable signet ring cell ... -
Characterization of gemcitabine loaded polyhydroxybutyrate coated magnetic nanoparticles for targeted drug delivery
(Bentham Science Publishers, 2020)Background: Targeted drug delivery is one of the recent hot topics in cancer therapy. Because of having a targeting potential under the magnetic field and a suitable surface for the attachment of different therapeutic ... -
The Cisplatin, 5-fluorouracil, Irinotecan, and Gemcitabine Treatment in Resistant 2D and 3D Model Triple Negative Breast Cancer Cell Line: ABCG2 Expression Data
(Bentham Scıence Publ Ltd, 2022)Background: Chemotherapeutics have been commonly used in cancer treatment. Objective: In this study, the effects of Cisplatin, 5-fluorouracil, Irinotecan, and Gemcitabine have been evaluated on two-dimensional (2D) (sensitive ... -
Cytogenetic Characteristics of Two Species of the Genus Pseudophoxinus Bleeker, 1860 (Cypriniformes: Leuciscidae) from Anatolia, Turkey
(Cytogenetic Characteristics of Two Species of the Genus Pseudophoxinus Bleeker, 1860 (Cypriniformes: Leuciscidae) from Anatolia, Turkey, 2022)The karyotypes of two Anatolian endemic leuciscid species, Pseudophoxinus alii Küçük, 2007 and P. elizavetae Bogutskaya, Küçük & Atalay, 2007, were studied using conventional cytogenetic methods. The diploid chromosome ... -
Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis
(BENTHAM SCIENCE PUBL LTD, 2016)Background: Despite development of novel cancer drugs, invasive ductal breast carcinoma and its metastasis are still highly morbid. Therefore, new therapeutic approaches are being developed and Hsp90 is an important target ... -
Determination of Potential Drug Candidate Molecules of the Hypericum perforatum for COVID-19 Treatment
(Springer Science and Business Media Deutschland GmbH, 2021)The novel human coronavirus was firstly emerged in December 2019 in Wuhan, China, and has spread rapidly around the world. There is no known specific effective treatment of COVID-19. The most commonly used agents against ... -
Determination of the effect of L. plantarum AB6-25, L. plantarum MK55 and S. boulardii T8-3C microorganisms on colon, cervix, and breast cancer cell lines: Molecular docking, and molecular dynamics study
(Elsevier B.V., 2022)Cancer constitutes an important part of the diseases that are caused all over the world. Due to the side effects of commonly used treatment options such as chemotherapy and radiotherapy, there has been a tendency to seek ... -
DETERMINATION OF THE RELATIONSHIP BETWEEN DOXORUBICIN RESISTANCE AND WNT SIGNALING PATHWAY IN HELA AND K562 CELL LINES
(EXCLI JOURNAL MANAGING OFFICE, 2018)Activation of the Wnt signaling in some types of cancer and its relation with chemotherapy resistance is a very interesting issue that has been emphasized in recent years. Although, it is known that increase in the activity ... -
Dextran-coated iron oxide nanoparticle for delivery of miR-29a to breast cancer cell line
(TAYLOR & FRANCIS LTD, 2019)In the last years, miRNAs have been associated with molecular pathways of cancer and other diseases. The change of expression level of miRNA has an inhibitory role in tumorigenesis. Nevertheless, the poor bioavailability ... -
Effect of bionanocomposites on human health
(Elsevier, 2022)Nanotechnology is a major scientific area that has important potential to produce innovative material and this technology especially shows itself in biomedical research. Bionanocomposites occur with conjugates of biopolymers ... -
The Effect of Gaussian Noise on Maximum Likelihood Fitting of Gompertz and Weibull Mortality Models with Yeast Lifespan Data
(TAYLOR & FRANCIS INC, 2019)Background/study context: Empirical lifespan data sets are often studied with the best-fitted mathematical model for aging. Here, we studied how experimental noises can influence the determination of the best-fitted aging ... -
Effect of PDYN and OPRK1 Polymorphisms on the Risk of Alcohol Use Disorder and the Intensity of Depressive Symptoms
(Oxford Unıv Press, 2023)Short Summary: OPRK1 rs6473797 CC genotype was found to lead to a 3.11 times greater alcohol dependence risk. OPRK1 rs963549 CC genotype was associated with the intensity of depressive symptoms. PDYN rs2281285, rs2225749 ...
