Güncel Gönderiler: Yayın Koleksiyonu
Toplam kayıt 36, listelenen: 21-36
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Alginate-based bionanocomposites for cancer therapy
(Elsevier, 2022)Alginate is a natural polymer widely produced by extraction from brown seaweeds. In recent years, the alginate-based systems have been designed and characterized as gels, matrices, membranes, beads, pellets, fibers, ... -
The Cisplatin, 5-fluorouracil, Irinotecan, and Gemcitabine Treatment in Resistant 2D and 3D Model Triple Negative Breast Cancer Cell Line: ABCG2 Expression Data
(Bentham Scıence Publ Ltd, 2022)Background: Chemotherapeutics have been commonly used in cancer treatment. Objective: In this study, the effects of Cisplatin, 5-fluorouracil, Irinotecan, and Gemcitabine have been evaluated on two-dimensional (2D) (sensitive ... -
The involvement of miRNAs in CYP450 gene expression: A brief review of the literature
(Marmara University, 2022)Drug biotransformation is a critical process in metabolic elimination of drugs. It occurs mainly in the liver as well as in other tissues such as kidney and small intestine and consists of three stages: Phase I, Phase II ... -
BRAF mutation in colorectal carcinomas with signet ring cell component
(CHINESE ANTI-CANCER ASSOC, 2017)Objective: Signet ring cell carcinoma is a rare subtype of colorectal carcinoma (CRC) with an associated BRAFV600E mutation. We investigated frequencies of BRAF mutation in 28 CRCs containing variable signet ring cell ... -
DETERMINATION OF THE RELATIONSHIP BETWEEN DOXORUBICIN RESISTANCE AND WNT SIGNALING PATHWAY IN HELA AND K562 CELL LINES
(EXCLI JOURNAL MANAGING OFFICE, 2018)Activation of the Wnt signaling in some types of cancer and its relation with chemotherapy resistance is a very interesting issue that has been emphasized in recent years. Although, it is known that increase in the activity ... -
Karyology of six cyprinid fishes from Seyhan and Ceyhan rivers in Anatolia
(TAYLOR & FRANCIS LTD, 2016)Karyological properties of Cyprinus carpio, Capoeta damascina, Luciobarbus pectoralis, Pseudophoxinus zekayi, Squalius seyhanensis and Alburnus adanensis from the Seyhan and Ceyhan river systems were investigated by examining ... -
Morphology and Histology of the Alimentary Canal of Epiphaneus malachiticus Boheman, 1842 (Coleoptera, Curculionidae)
(Pleiades Publishing, 2019)This study is aimed at describing the morphological and histological structures of the alimentary canal in the adults of Epiphaneus malachiticus Boheman, 1842 (Coleoptera: Curculionidae), a poorly investigated species of ... -
Folic acid functionalized PEG coated magnetic nanoparticles for targeting anti-cancer drug delivery: Preparation, characterization and cytotoxicity on Doxorubicin, Zoledronic acid and Paclitaxel resistant MCF-7 breast cancer cell lines
(TAYLOR & FRANCIS INC, 2018)In this study, MNPs were synthesized, coated with biocompatible polyethylene glycol (PEG) and conjugated with folic acid. Crystal and chemical structures, shape, size and magnetic properties of synthesized nanoparticles ... -
Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis
(BENTHAM SCIENCE PUBL LTD, 2016)Background: Despite development of novel cancer drugs, invasive ductal breast carcinoma and its metastasis are still highly morbid. Therefore, new therapeutic approaches are being developed and Hsp90 is an important target ... -
Multiplex Detection of Aspergillus fumigatus Mycoviruses
(MDPI, 2018)Mycoviruses are viruses that naturally infect and replicate in fungi. They are widespread in all major fungal groups including plant and animal pathogenic fungi. Several dsRNA mycoviruses have been reported in Aspergillus ... -
The secondary metabolites produced by Lactobacillus plantarum downregulate BCL-2 and BUFFY genes on breast cancer cell line and model organism Drosophila melanogaster: molecular docking approach
PurposeThe current study was designed to evaluate the toxicity of the secondary metabolites of Lactobacillus plantarum against the human breast cancer cell line (MCF-7) and the Drosophila melanogaster.MethodsIn this study, ... -
New records of Pseudophoxinus firati from Turkey (Teleostei: Leuciscidae)
(WILEY, 2019)Pseudophoxinus firati was described from one spring in the upper Euphrates River drainage in Turkey. Here we record this species from seven additional sites, three in the upper Euphrates drainage, one in the upper Seyhan ... -
Investigation of Structural, Vibrational Properties and Electronic Structure of Fluorene-9-Bisphenol: A DFT Approach
(WILEY-V C H VERLAG GMBH, 2018)Bisphenol A (BPA) is a chemical used in a variety of materials and has adverse effects on endocrine system. The substitutes of BPA have been developed to produce BPA-free plastics. Fluorene-9-bisphenol (BPFL), has ... -
The physical studies and interaction with anti-apoptotic proteins of 2-(bis(cyanomethyl)amino)-2-oxoethyl methacrylate molecule
(INST CONDENSED MATTER PHYSICS NATL ACAD SCIENCES UKRAINE, 2019)In this work 2-(bis(cyanomethyl) amino)-2-oxoethyl methacrylate (CMA2OEM) molecule has been characterized theoretically. First, the potential energy surface has been calculated to find the lowest energy state of the molecule. ... -
Dextran-coated iron oxide nanoparticle for delivery of miR-29a to breast cancer cell line
(TAYLOR & FRANCIS LTD, 2019)In the last years, miRNAs have been associated with molecular pathways of cancer and other diseases. The change of expression level of miRNA has an inhibitory role in tumorigenesis. Nevertheless, the poor bioavailability ... -
The Effect of Gaussian Noise on Maximum Likelihood Fitting of Gompertz and Weibull Mortality Models with Yeast Lifespan Data
(TAYLOR & FRANCIS INC, 2019)Background/study context: Empirical lifespan data sets are often studied with the best-fitted mathematical model for aging. Here, we studied how experimental noises can influence the determination of the best-fitted aging ...